Psychiatry and Psychology

At Service Hospitalier Frédéric Joliot – CEA, clinical research in mental disorders focuses on severe major depressive disorder and schizophrenia, with studies designed to better understand symptoms and brain changes linked to treatment response and disease biology.

  • Testing a new approach to improve depressive symptoms in hospitalized patients with severe depression
  • Exploring brain-based markers that may track recovery and treatment effects in depression
  • Studying neuroinflammation and genetic factors in schizophrenia

This research combines psychiatry with advanced PET imaging and other diagnostic tools to support more precise diagnosis and treatment monitoring.

Nervous System Diseases

The site conducts research on several nervous system diseases, including Alzheimer’s disease, multiple sclerosis, Huntington’s disease, and epilepsy, with a strong emphasis on understanding how these conditions progress in the brain.

  • Mapping tau-related brain changes in Alzheimer’s pathology
  • Measuring inflammatory activity in multiple sclerosis
  • Identifying biomarkers that may predict Huntington’s disease progression
  • Improving seizure focus localization in drug-resistant epilepsy

These studies aim to improve diagnosis, guide care decisions, and support earlier detection of disease-related changes through neuroimaging and biomarker research.

Neoplasms and Oncology Imaging

Research in neoplasms at this French Alternative Energies And Atomic Energy Commision site includes imaging-based studies in patients with polymetastatic solid cancers, reflecting a broader effort to understand how cancer behaves and how it responds to treatment.

  • Studying imaging signals linked to tumor activity
  • Assessing how advanced scans can support cancer evaluation
  • Exploring ways to improve monitoring of disease spread and treatment impact

The work centers on diagnostic techniques and investigative imaging that may strengthen cancer assessment in clinical practice.

Analytical, Diagnostic and Therapeutic Techniques and Equipment

A major part of the research program at Service Hospitalier Frédéric Joliot – CEA is dedicated to analytical and diagnostic techniques, especially advanced brain imaging used to study disease mechanisms and treatment effects across neurological and psychiatric conditions.

  • Evaluating PET and MRI methods for better disease detection
  • Using imaging to compare treatment effects and biological changes
  • Developing tools that may improve localization, monitoring, and prognosis

This area supports research across anesthesia and analgesia, investigative techniques, and broader clinical imaging applications aimed at making diagnosis and follow-up more accurate.