Alzheimer’s Disease Research

At Brain Research Center Amsterdam B.V., a major share of the clinical research focuses on Nervous System Diseases, especially Alzheimer’s disease and related cognitive disorders. These studies are designed to test new therapies, track disease-related biomarkers, and better understand how to slow memory and thinking decline.

  • Early and mild to moderate Alzheimer’s disease
  • Dominantly inherited Alzheimer disease and early-onset forms
  • Biomarker and cognition-focused studies for disease progression

The research includes efforts to improve treatment effectiveness and identify measurable signs of brain change that may support earlier and more precise care.

Parkinson’s Disease Studies

The site also runs trials in Parkinson’s disease, reflecting its strong focus on neurology and movement-related disorders. These studies aim to evaluate whether new treatments can help slow symptom worsening and support daily functioning in people living with early-stage disease.

  • Early Parkinson’s disease
  • Movement and functional outcomes
  • Testing potential disease-modifying therapies

This work helps explore whether emerging therapies can improve long-term disease control and quality of life.

Cardiovascular Disease Research

Alongside brain-focused studies, the center participates in trials on cardiovascular diseases, including heart failure, hypertension, and broader cardiovascular disease risk. These trials are intended to assess whether new treatment approaches can reduce serious heart-related events and improve prevention.

  • Prevention of heart failure
  • Type 2 diabetes with cardiovascular risk
  • Reducing cardiovascular death and related complications

The research supports better strategies for patients with overlapping metabolic and heart conditions.

Mental Health and Cognitive Symptoms

Clinical trials at this Amsterdam site also cover Psychiatry and Psychology, with a focus on major depressive disorder and cognitive symptoms linked to brain disease. These studies are aimed at evaluating new options that may improve mood, thinking, and everyday functioning.

  • Major depressive disorder
  • Cognitive and global functioning outcomes
  • Assessing safety and benefit of new adjunctive treatments

This area adds an important mental health dimension to the center’s broader neurological research portfolio.