Clinical trials on Insulin Resistance

  • CT-EU-00114534

    Comparing Acupuncture and Metformin with Lifestyle Changes for PCOS and Insulin Resistance

    This clinical trial is designed to explore the effectiveness of two different treatments for women with Polycystic Ovary Syndrome (PCOS) who are also experiencing insulin resistance. The study aims to compare the impact of combining lifestyle management with either acupuncture or metformin (a medication), against the effects of lifestyle management alone. The main goal is to see how these treatments can improve the body’s ability to manage glucose, which is crucial in preventing the development of type 2 diabetes.

    The trial will last for 4 months, during which the researchers will closely monitor changes in insulin sensitivity, glucose regulation, and overall health markers including hormone levels, body fat distribution, and mental health aspects such as anxiety and depression. One of the unique aspects of this study is its focus on not just the physical health outcomes, but also on the quality of life and emotional well-being of the participants.

    For those considering the metformin treatment, it’s important to note that the medication will be gradually introduced to minimize side effects, starting with a lower dose and increasing to the target dose over the first three weeks. The study also places a strong emphasis on the potential benefits of acupuncture, hypothesizing that it could be equally effective as metformin but with fewer negative side effects.

    This trial is particularly significant for women with PCOS and insulin resistance, as it seeks to provide evidence-based insights into managing these conditions, improving fertility, and potentially preventing the onset of more serious health issues down the line.

    • metformin