Clinical trials on Growth Hormone Deficiency

  • CT-EU-00112260

    Growth Hormone Therapy Study for Cognitive Improvement in Retired Football Players

    The study aims to investigate the potential benefits of growth hormone (GH) therapy on cognitive functions such as memory, attention, and other mental capabilities in retired professional football players with growth hormone deficiency (GHD). GHD is the most common anterior pituitary abnormality after traumatic brain injury (TBI).

    The study will assign participants to either receive growth hormone treatment or a placebo randomly, ensuring that neither the participants nor the researchers know which group each participant is in to maintain unbiased results. Following the initial phase, there is an open-label extension where all participants are offered the growth hormone treatment.

    The focus of the research is on evaluating the effects of the therapy on working memory, processing speed, executive function, verbal learning, and memory—key aspects of cognitive function that significantly impact daily living and overall quality of life. Various tools, including questionnaires and specific tests for cognitive performance assessment, will be employed to measure these effects.

    This research presents an opportunity for retired professional football players experiencing cognitive difficulties from brain injuries to explore potential improvements to their cognitive health. Participation in the study not only offers a chance for personal cognitive enhancement but also contributes to the broader knowledge base that could benefit others facing similar challenges.

    • somatropin