Clinical trials on Chronic Renal Failure

  • CT-EU-00111425

    Understanding the Impact of Antiphospholipid Antibodies on Vascular Health in Chronic Kidney Disease Patients

    This clinical trial is focused on understanding how a condition known as endothelial dysfunction, which affects the blood vessels, is influenced by antiphospholipid antibodies in patients undergoing hemodialysis due to chronic renal failure. The study aims to explore the connection between these antibodies, the health of blood vessels, and complications related to arteriovenous fistula—a common vascular access for hemodialysis patients.

    To assess the health of your blood vessels, we use a non-invasive test called the “Flow Mediated Dilation” (FMD) test. This test measures how well your blood vessels can expand in response to increased blood flow, which is an indicator of their health. The study will also look into various factors that might affect the health of your blood vessels, including the levels of certain substances in your blood and urine, such as nitric oxide and endothelin, which play roles in blood vessel function.

    By participating, you’ll contribute to research that could help improve the understanding of how chronic kidney disease and hemodialysis affect blood vessel health, potentially leading to better management of vascular access and reducing complications. This study is especially relevant if you’re undergoing hemodialysis and are interested in how your condition might be affecting your blood vessels and overall cardiovascular health.