West Nile viral infection – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Wed, 27 May 2026 13:12:11 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png West Nile viral infection – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A Study of Doravirine for Early Treatment of West Nile Virus Infection in Patients at Risk of Disease Worsening https://clinicaltrials.eu/trial/a-study-of-doravirine-for-early-treatment-of-west-nile-virus-infection-in-patients-at-risk-of-disease-worsening/ Thu, 30 Apr 2026 13:08:17 +0000 https://clinicaltrials.eu/trial/a-study-of-doravirine-for-early-treatment-of-west-nile-virus-infection-in-patients-at-risk-of-disease-worsening/ This clinical trial is studying West Nile Virus Infection, which is an illness caused by a virus that is typically spread through mosquito bites. In some people, this infection can lead to more serious complications, particularly in those who have certain risk factors. The treatment being tested in this study is doravirine, which is given as film-coated tablets taken by mouth. Some participants will receive doravirine while others will receive standard care, which means the usual treatment approach currently used for this condition.

The purpose of this study is to find out whether doravirine can help reduce the amount of virus in the blood more quickly in people who have West Nile Virus infection and are at risk of the disease getting worse. The study will look at how fast the virus levels drop in patients who take doravirine compared to those who receive standard care. The study will also examine whether doravirine helps fever go away more quickly.

Participants in this study will be assigned randomly to either receive doravirine or standard care. Those taking doravirine will take 100 milligrams once daily for up to five days. During the study, blood tests will be done to measure the virus levels in the blood. The study is designed to test whether this medication can help prevent the infection from progressing to more serious forms of the disease in people who are at higher risk.

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