Vestibular disorder – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Tue, 23 Jun 2026 04:03:38 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Vestibular disorder – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A Study of Prednisolone Compared to Placebo for Patients with Vestibular Neuritis to Evaluate Effects on Balance and Dizziness Symptoms https://clinicaltrials.eu/trial/a-study-of-prednisolone-compared-to-placebo-for-patients-with-vestibular-neuritis-to-evaluate-effects-on-balance-and-dizziness-symptoms/ Thu, 30 Apr 2026 13:08:38 +0000 https://clinicaltrials.eu/trial/a-study-of-prednisolone-compared-to-placebo-for-patients-with-vestibular-neuritis-to-evaluate-effects-on-balance-and-dizziness-symptoms/ This study is looking at vestibular neuritis, which is a condition that affects the inner ear and causes sudden spinning sensations or a feeling of being off balance, along with dizziness. These symptoms happen because of inflammation in the nerve that helps control balance. The study will test whether a medicine called prednisolone can help reduce these balance and dizziness symptoms. Prednisolone is a type of steroid medicine that reduces inflammation in the body. Some participants will receive prednisolone tablets while others will receive placebo. The purpose of the study is to see if a 10-day treatment with prednisolone, where the dose is gradually reduced over time, works better than placebo at improving symptoms in people with vestibular neuritis.

Participants in this study will be randomly assigned to receive either prednisolone or placebo for 10 days. The study is designed so that neither the participants nor the doctors will know who is receiving which treatment. To make the treatments look the same, the prednisolone tablets will be placed inside capsules. During the study, participants will be asked to complete questionnaires that measure dizziness and balance symptoms, as well as how these symptoms affect daily life and overall quality of life. These questionnaires will be completed at different times: 2 weeks, 6 weeks, 3 months, and 12 months after starting the treatment.

The study will also include tests to measure how well the balance system is working. These include a video test that measures eye movements when the head is moved quickly, a timed walking test, measurements of body movement while standing and walking, and a test of standing on a foam pad. Some of these tests will be done at the beginning of the study and again at 6 weeks to see if there are any changes. The main focus will be on comparing the dizziness symptom scores between the two groups at 6 weeks after treatment starts. The study will also look at healthcare use and time off work to understand the broader impact of the treatment.

]]> A study to evaluate the use of levothyroxine sodium in patients with sudden onset of dizziness caused by inner ear issues. https://clinicaltrials.eu/trial/a-study-to-evaluate-the-use-of-levothyroxine-sodium-in-patients-with-sudden-onset-of-dizziness-caused-by-inner-ear-issues/ Wed, 29 Apr 2026 15:09:48 +0000 https://clinicaltrials.eu/trial/a-study-to-evaluate-the-use-of-levothyroxine-sodium-in-patients-with-sudden-onset-of-dizziness-caused-by-inner-ear-issues/ This study investigates the treatment of acute unilateral vestibulopathy, a condition that affects the inner ear and causes sudden dizziness or a spinning sensation known as vertigo. The research aims to determine if the medication levothyroxine sodium can improve the quality of life for individuals experiencing these symptoms. Participants will receive either the active medication or a placebo.

The investigation is conducted using a double-blind method, meaning that neither the participants nor the researchers know which specific treatment is being administered to prevent bias. During the study, individuals will take a tablet daily for a period of time to observe how the treatment influences their ability to function in daily life and their overall sense of balance.

]]> Study on Meniere’s Disease: Comparing Methylprednisolone and Placebo for Patients with Unilateral Meniere’s Disease https://clinicaltrials.eu/trial/study-on-menieres-disease-comparing-methylprednisolone-and-placebo-for-patients-with-unilateral-menieres-disease/ Wed, 29 Apr 2026 14:24:16 +0000 https://clinicaltrials.eu/trial/study-on-menieres-disease-comparing-methylprednisolone-and-placebo-for-patients-with-unilateral-menieres-disease/ This clinical trial is focused on studying the effects of a treatment for Menière’s disease, a condition that affects the inner ear and can cause episodes of vertigo, which is a sensation of spinning or dizziness. The treatment being tested is an injection of methylprednisolone, a type of medication known as a corticosteroid, which is used to reduce inflammation and suppress the immune system. The trial aims to determine if methylprednisolone is more effective than a placebo in reducing the frequency of vertigo attacks in patients with Menière’s disease.

Participants in the study will receive injections directly into the ear, a method known as intratympanic injection. The study will compare the effects of methylprednisolone with those of a placebo over a period of one year. The goal is to see if the treatment can provide better control over vertigo attacks compared to not receiving the active medication. The study will also monitor the quality of life of participants, including aspects related to dizziness and tinnitus, which is a ringing or buzzing noise in one or both ears that may be associated with Menière’s disease.

In addition to methylprednisolone, the study will also consider the use of other medications such as dexamethasone, triamcinolone, and gentamicin, which are also administered through intratympanic injections. The study will track the frequency of these injections and assess their impact on hearing and overall well-being. The trial will also evaluate the use of metoclopramide, a medication that can help manage nausea and vomiting, which are common symptoms during vertigo attacks. The study is designed to provide valuable insights into the effectiveness and safety of these treatments for managing Menière’s disease.

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