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Trisomy 21

  • Study of AEF0217 compared to placebo for improving behavior and thinking skills in adults and older adolescents with Down syndrome

    Recruiting

    2 1
    Investigated Drugs:
    • 1-((3S,8S,9S,10R,13S,14S,17S)3-BENZYLOXY-10,13,17-TRIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1HCYCLOPENTA[A]PHENANTHRENE-17-YL)ETHAN-1-ONE
    France Italy Spain

  • Study on the Use of 18F-PI-2620 to Detect Alzheimer’s in People with Down Syndrome

    Recruiting

    2 1 1
    Investigated Diseases:
    • Trisomy 21
    • Dementia Alzheimer’s type
    Investigated Drugs:
    • Izaflortaucipir (18F)
    Spain

  • Study of levetiracetam to prevent seizures in adults who have both Down syndrome and Alzheimer’s disease

    Recruiting

    3 1 1
    Investigated Diseases:
    • Trisomy 21
    • Dementia Alzheimer’s type
    Investigated Drugs:
    • Levetiracetam
    Spain

  • Study on Bumetanide for Improving Cognitive Function in Children and Adolescents with Down Syndrome

    Recruiting

    2 1 1
    Investigated Diseases:
    • Trisomy 21
    Investigated Drugs:
    • BUMETANIDE
    Italy

  • Study on Sleep and Temperature Changes in Alzheimer’s Disease for Down Syndrome Patients Using Izaflortaucipir (18F)

    Recruiting

    2 1 1
    Investigated Diseases:
    • Trisomy 21
    • Dementia Alzheimer’s type
    Investigated Drugs:
    • Izaflortaucipir (18F)
    Spain

  • Study of Cytarabine and Daunorubicin for Treating Myeloid Leukemia in Children with Down Syndrome

    Not yet recruiting

    3 1 1 1
    Investigated Diseases:
    • Trisomy 21
    • Acute myeloid leukaemia
    Investigated Drugs:
    • Daunorubicin
    • Cytarabine
    Austria Belgium Czechia Germany Italy The Netherlands +1

Investigational Drugs in This Location

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European Clinical Trials Information Network

The European Clinical Trials Information Network is transforming access to clinical trial information for patients across Europe. By overcoming language barriers, our platform allows everyone, regardless of their native language, to easily find relevant and comprehensible clinical trial data. This innovative service connects patients to cutting-edge treatments, creating a unified European community where health and progress transcend borders.

This service is not affiliated with the European Commission, the EMA, or the official CTIS system. Most information comes from publicly available international clinical-trial registries, supplemented by data from academic centres, national regulators, and commercial sponsors. We aim to keep all content accurate and up to date.

Explore the full ecosystem of clinical research in Europe.

The information provided on this website is mainly derived from international public clinical trial databases (CTIS.eu). In addition, we are including supplementary sources, such as information provided by academic centers and national regulators, as well as information supplied by commercial sponsors (pharmaceutical companies and contract research organizations). We try to ensure that the information provided is accurate and up to date.

Certain content and visual elements on this website have been generated or enhanced using artificial intelligence (AI).

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