Trigeminal neuralgia – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:28:50 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Trigeminal neuralgia – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effectiveness of Botulinum Toxin A and Sodium Chloride for Patients with Trigeminal Neuralgia https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-botulinum-toxin-a-and-sodium-chloride-for-patients-with-trigeminal-neuralgia/ Wed, 29 Apr 2026 14:23:37 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-botulinum-toxin-a-and-sodium-chloride-for-patients-with-trigeminal-neuralgia/ This clinical trial is focused on studying the safety and effectiveness of a treatment for trigeminal neuralgia, a condition that causes severe facial pain. The treatment being tested is botulinum toxin A, commonly known as Botox. Botox is a protein that, when injected, can help relax muscles and reduce pain. In this study, Botox will be compared to a placebo to see if it is more effective in relieving the pain associated with trigeminal neuralgia.

The purpose of the study is to determine if Botox can provide better pain relief than a placebo for patients suffering from trigeminal neuralgia. Participants in the study will receive injections of either Botox or a placebo. The study will monitor the participants over a period of time to assess changes in their pain levels and any side effects they may experience. The study will also look at certain biological markers in the body that might predict how well the treatment works.

Throughout the study, participants will be evaluated to see how their pain changes from the beginning to the end of the trial. The study will also explore whether there are differences in certain biological markers between those who respond well to the treatment and those who do not. This research aims to provide valuable insights into the potential benefits of using Botox for managing trigeminal neuralgia and to identify factors that might influence its effectiveness.

]]> Study on Basimglurant for Treating Pain in Patients with Trigeminal Neuralgia https://clinicaltrials.eu/trial/study-on-basimglurant-for-treating-pain-in-patients-with-trigeminal-neuralgia/ Wed, 29 Apr 2026 14:22:57 +0000 https://clinicaltrials.eu/trial/study-on-basimglurant-for-treating-pain-in-patients-with-trigeminal-neuralgia/ This clinical trial is focused on studying the treatment of Trigeminal Neuralgia, a condition that causes severe facial pain. The study will use a medication called Basimglurant, which is taken in capsule form. The purpose of the study is to evaluate the safety and effectiveness of Basimglurant in reducing pain for patients who have not had sufficient relief from their current pain treatments.

The study will begin with an 8-week period where participants will start taking Basimglurant daily. This is followed by a 12-week phase where participants will continue taking the medication or a placebo, without knowing which one they are receiving. This is to help understand how well the medication works compared to no active treatment. After this, there is a 52-week period where all participants will receive Basimglurant to further assess its long-term safety and effectiveness.

Throughout the study, participants will be monitored for any changes in their pain levels and overall health. The study aims to provide valuable information on how Basimglurant can help manage pain associated with Trigeminal Neuralgia and improve the quality of life for those affected by this condition.

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