Tooth disorder – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:28:09 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Tooth disorder – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on High-Dosage Fluoride Toothpaste for Patients with Dental Root Caries https://clinicaltrials.eu/trial/study-on-high-dosage-fluoride-toothpaste-for-patients-with-dental-root-caries/ Wed, 29 Apr 2026 15:05:27 +0000 https://clinicaltrials.eu/trial/study-on-high-dosage-fluoride-toothpaste-for-patients-with-dental-root-caries/ This clinical trial is focused on studying the effects of using a high-dosage fluoride toothpaste to control dental root caries, which are cavities that form on the roots of teeth. The study compares a high-dosage fluoride toothpaste, specifically Duraphat with a fluoride concentration of 5,000 parts per million (ppm), to a normal fluoride toothpaste with a concentration of 1,450 ppm. The aim is to see if the higher concentration of fluoride can better stop the development of root caries and prevent new ones from forming, even without the usual cleaning of the teeth to remove plaque.

The trial involves using these toothpastes on experimental samples to observe the effects on dental root health. The main focus is on how much mineral is lost or gained in the dental roots when using these toothpastes. Additionally, the study will measure the amount of fluoride present in saliva and the plaque that forms on the dental roots. This research is important for understanding how different fluoride concentrations can impact dental health, particularly in preventing and controlling root caries.

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