Tinnitus – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Tue, 23 Jun 2026 04:03:38 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Tinnitus – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Botulinum Toxin A for Tinnitus in Patients with Bruxism or Jaw Muscle Pain https://clinicaltrials.eu/trial/study-on-botulinum-toxin-a-for-tinnitus-in-patients-with-bruxism-or-jaw-muscle-pain/ Wed, 29 Apr 2026 15:04:45 +0000 https://clinicaltrials.eu/trial/study-on-botulinum-toxin-a-for-tinnitus-in-patients-with-bruxism-or-jaw-muscle-pain/ This clinical trial is focused on studying the effects of a treatment for patients who have tinnitus, a condition where individuals hear ringing or other noises in one or both ears. The study is particularly interested in those who also experience bruxism (teeth grinding) and/or jaw muscle myalgia (muscle pain in the jaw). The treatment being tested is an injection of Botulinum toxin type A, commonly known as BOTOX. This study will compare the effects of BOTOX injections to a placebo to see if it can help reduce the symptoms of tinnitus, bruxism, and jaw muscle pain.

The purpose of the study is to explore whether BOTOX can improve the quality of life for those suffering from these conditions. Participants will receive injections and will be monitored over a period of time to assess any changes in their symptoms. The study will involve a series of visits where participants will receive either the BOTOX treatment or a placebo, and their progress will be tracked through questionnaires and assessments.

Throughout the study, participants will be asked to report on their tinnitus symptoms, headache levels, and jaw muscle pain. The study aims to determine if there is a significant difference in symptom improvement between those receiving the BOTOX treatment and those receiving the placebo. This research hopes to provide new insights into managing tinnitus and related conditions effectively.

]]> Study on Meniere’s Disease: Comparing Methylprednisolone and Placebo for Patients with Unilateral Meniere’s Disease https://clinicaltrials.eu/trial/study-on-menieres-disease-comparing-methylprednisolone-and-placebo-for-patients-with-unilateral-menieres-disease/ Wed, 29 Apr 2026 14:24:16 +0000 https://clinicaltrials.eu/trial/study-on-menieres-disease-comparing-methylprednisolone-and-placebo-for-patients-with-unilateral-menieres-disease/ This clinical trial is focused on studying the effects of a treatment for Menière’s disease, a condition that affects the inner ear and can cause episodes of vertigo, which is a sensation of spinning or dizziness. The treatment being tested is an injection of methylprednisolone, a type of medication known as a corticosteroid, which is used to reduce inflammation and suppress the immune system. The trial aims to determine if methylprednisolone is more effective than a placebo in reducing the frequency of vertigo attacks in patients with Menière’s disease.

Participants in the study will receive injections directly into the ear, a method known as intratympanic injection. The study will compare the effects of methylprednisolone with those of a placebo over a period of one year. The goal is to see if the treatment can provide better control over vertigo attacks compared to not receiving the active medication. The study will also monitor the quality of life of participants, including aspects related to dizziness and tinnitus, which is a ringing or buzzing noise in one or both ears that may be associated with Menière’s disease.

In addition to methylprednisolone, the study will also consider the use of other medications such as dexamethasone, triamcinolone, and gentamicin, which are also administered through intratympanic injections. The study will track the frequency of these injections and assess their impact on hearing and overall well-being. The trial will also evaluate the use of metoclopramide, a medication that can help manage nausea and vomiting, which are common symptoms during vertigo attacks. The study is designed to provide valuable insights into the effectiveness and safety of these treatments for managing Menière’s disease.

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