Thrombectomy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Wed, 17 Jun 2026 04:02:13 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Thrombectomy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of cangrelor with mechanical thrombectomy in patients with acute ischemic stroke selected by perfusion imaging https://clinicaltrials.eu/trial/study-on-cangrelor-and-mechanical-thrombectomy-for-acute-ischemic-stroke-patients-selected-by-perfusion-imaging/ Wed, 29 Apr 2026 15:01:07 +0000 https://clinicaltrials.eu/trial/study-on-cangrelor-and-mechanical-thrombectomy-for-acute-ischemic-stroke-patients-selected-by-perfusion-imaging/ This study focuses on patients with acute ischemic stroke, a condition where blood flow to the brain is blocked by a clot. The research examines the effectiveness of combining two treatments: mechanical thrombectomy (a procedure to remove blood clots) and a blood-thinning medication called cangrelor. The medication is given through an intravenous infusion directly into the bloodstream.

The purpose of this research is to determine if adding cangrelor to the standard mechanical thrombectomy treatment can improve recovery outcomes for stroke patients. The study involves patients who arrive at the hospital within 24 hours of their stroke symptoms beginning and who show specific patterns on their brain imaging scans.

During the study, participants will be divided into two groups. One group will receive the standard mechanical thrombectomy treatment plus cangrelor, while the other group will receive only mechanical thrombectomy. The maximum daily dose of cangrelor will be 150 milligrams, and the treatment will last for one day. Doctors will monitor patients’ recovery and brain function over three months to determine how well the combined treatment works.

]]> Study on Erythromycin Lactobionate for Improving Gastric Emptying in Stroke Patients Needing Mechanical Thrombectomy https://clinicaltrials.eu/trial/study-on-erythromycin-lactobionate-for-improving-gastric-emptying-in-stroke-patients-needing-mechanical-thrombectomy/ Wed, 29 Apr 2026 14:57:06 +0000 https://clinicaltrials.eu/trial/study-on-erythromycin-lactobionate-for-improving-gastric-emptying-in-stroke-patients-needing-mechanical-thrombectomy/ This clinical trial focuses on patients who have experienced an ischemic stroke, a condition where blood flow to the brain is blocked, often requiring urgent medical procedures. The study investigates the use of erythromycin lactobionate, a medication administered through an intravenous infusion, to help manage the stomach contents of these patients. Specifically, the trial aims to see if this medication can reduce the size of the stomach area, as measured by an ultrasound, before patients undergo a procedure called mechanical thrombectomy, which is used to remove the blood clot causing the stroke.

The purpose of the study is to evaluate how effective erythromycin lactobionate is in decreasing the stomach’s antral surface area, which is the part of the stomach closest to the small intestine. This is important because having a full stomach can complicate medical procedures. Patients who are found to have significant stomach contents, as determined by an ultrasound scan, will be included in the study. The trial will monitor changes in the stomach area before and after the thrombectomy procedure to assess the medication’s impact.

Throughout the study, various observations will be made, such as the frequency of patients with reduced stomach size and any changes in medical management strategies due to the ultrasound findings. The trial will also track any complications that may arise during the thrombectomy procedure, such as low blood pressure or breathing difficulties, and any side effects related to the administration of erythromycin lactobionate. The study is designed to provide valuable insights into the potential benefits of using this medication in stroke patients undergoing emergency procedures.

]]> Study on the Effectiveness of Alteplase as an Add-On to Mechanical Thrombectomy for Patients with Acute Ischemic Stroke https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-alteplase-as-an-add-on-to-mechanical-thrombectomy-for-patients-with-acute-ischemic-stroke/ Wed, 29 Apr 2026 14:26:29 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-alteplase-as-an-add-on-to-mechanical-thrombectomy-for-patients-with-acute-ischemic-stroke/ This clinical trial is focused on patients who have experienced an acute ischemic stroke, a condition where blood flow to a part of the brain is blocked, often by a blood clot. The study is investigating the use of a medication called Alteplase, also known by its code name rt-PA, as an additional treatment to a procedure called mechanical thrombectomy. Mechanical thrombectomy is a method used to physically remove the clot from the blood vessel in the brain. The goal of the study is to determine if adding Alteplase can improve the outcomes for patients who have already undergone this procedure and have achieved a significant reopening of the blocked blood vessel.

Participants in the study will receive either the medication or a placebo after their mechanical thrombectomy procedure. The study will monitor the patients over a period of time to assess the effects of the treatment. This includes checking the blood flow in the brain using imaging techniques like CT Perfusion, which is a type of scan that shows how blood is moving through the brain. The study will also evaluate the patients’ recovery and ability to perform daily activities after 90 days.

The purpose of this research is to explore whether the combination of mechanical thrombectomy and Alteplase can lead to better recovery outcomes for patients who have suffered an acute ischemic stroke. By understanding the potential benefits of this treatment approach, the study aims to improve the care and recovery of stroke patients in the future.

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