Tendon injury – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:14:15 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Tendon injury – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Zoledronic Acid for Healing After Rotator Cuff Surgery in Patients with Tendon Rupture and Osteoporosis https://clinicaltrials.eu/trial/study-on-zoledronic-acid-for-healing-after-rotator-cuff-surgery-in-patients-with-tendon-rupture-and-osteoporosis/ Wed, 29 Apr 2026 15:02:53 +0000 https://clinicaltrials.eu/trial/study-on-zoledronic-acid-for-healing-after-rotator-cuff-surgery-in-patients-with-tendon-rupture-and-osteoporosis/ This clinical trial is focused on studying the effects of a medication called Zoledronic Acid on the healing process after surgery for a shoulder condition known as a chronic rotator cuff tear. This condition involves a tear in the tendons around the shoulder joint, which can occur due to injury or wear and tear over time. The study also considers patients with osteoporosis, a condition where bones become weak and fragile. The purpose of the study is to see if Zoledronic Acid can help improve the healing of the tendon after it has been repaired through a procedure called arthroscopic surgery, which is a minimally invasive surgery using small incisions and a camera to guide the repair.

Participants in the study will receive either Zoledronic Acid or a placebo, which is a substance with no active medication, to compare the effects. The medication will be given through an infusion, which means it is delivered directly into the bloodstream via a vein. The study will monitor the healing of the tendon using magnetic resonance imaging (MRI), a type of scan that uses magnets and radio waves to create detailed images of the inside of the body. These scans will be done at several points over a period of up to five years after the surgery to assess the integrity of the tendon and see if it has healed properly without re-tearing.

In addition to the primary focus on tendon healing, the study will also look at other factors such as muscle condition, shoulder movement, strength, and pain levels. These will be evaluated using various scores and assessments to provide a comprehensive view of the shoulder’s recovery. The study aims to provide valuable insights into whether Zoledronic Acid can be a beneficial addition to the treatment plan for individuals undergoing surgery for chronic rotator cuff tears, particularly those who also have osteoporosis.

]]> Study on Hyperbaric Oxygen Therapy for Acute Hamstring Injury in Athletes and Military Personnel https://clinicaltrials.eu/trial/study-on-hyperbaric-oxygen-therapy-for-acute-hamstring-injury-in-athletes-and-military-personnel/ Wed, 29 Apr 2026 14:30:02 +0000 https://clinicaltrials.eu/trial/study-on-hyperbaric-oxygen-therapy-for-acute-hamstring-injury-in-athletes-and-military-personnel/ This clinical trial is focused on studying the effects of a treatment called Hyperbaric Oxygen Therapy on individuals with an acute hamstring injury. An acute hamstring injury is a sudden injury to the muscles at the back of the thigh, often causing pain and difficulty in movement. The treatment involves using oxygen in a special way, where it is delivered under higher pressure than normal, which is believed to help in healing the injury faster.

The study will use two forms of oxygen: Conoxia, 100% v/v, medicinal gas, compressed and Conoxia® Vloeibaar, 100% v/v, medicinal gas, cryogenic. Both forms of oxygen are administered through inhalation, meaning participants will breathe in the oxygen. The main goal of the study is to compare how quickly athletes and military personnel can return to their activities after receiving this treatment, compared to those who receive standard care.

Participants in the study will undergo seven daily sessions of hyperbaric oxygen therapy. The study will also collect information on various aspects of recovery, such as pain levels, physical examination results, and MRI findings, which is a type of imaging that helps visualize the injury. Additionally, the study will monitor for any re-injuries and any adverse events that may occur during the treatment period. The trial aims to provide insights into whether this therapy can effectively speed up recovery from hamstring injuries.

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