Stevens-Johnson syndrome – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:02:33 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Stevens-Johnson syndrome – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Filgrastim for Patients with Severe Bullous Drug Eruptions: Lyell and Stevens-Johnson Syndromes https://clinicaltrials.eu/trial/study-on-filgrastim-for-patients-with-severe-bullous-drug-eruptions-lyell-and-stevens-johnson-syndromes/ Wed, 29 Apr 2026 15:00:47 +0000 https://clinicaltrials.eu/trial/study-on-filgrastim-for-patients-with-severe-bullous-drug-eruptions-lyell-and-stevens-johnson-syndromes/ This clinical trial is focused on studying the effects of a medication called filgrastim in treating severe skin reactions known as Stevens-Johnson syndrome and Lyell syndrome. These conditions can cause painful skin rashes and blisters, and in severe cases, can lead to large areas of skin peeling off. The study aims to see if adding filgrastim to the usual treatment can help stop the progression of these skin conditions more effectively than the usual treatment alone.

Participants in the study will be divided into two groups. One group will receive the standard treatment for these skin conditions along with filgrastim, while the other group will receive the standard treatment with a placebo. The study will last for a period of five days, during which the main focus will be on whether the skin condition stops getting worse. The study will also look at other factors, such as how quickly the skin heals, the overall health of participants after 30 days and one year, and any side effects experienced during the study.

The medication filgrastim is given as an injection or infusion, which means it is administered directly into the body through a needle. Another substance used in the study is glucose monohydrate, which is a type of sugar solution often used in medical treatments. The goal of the study is to determine if filgrastim can provide additional benefits in treating these severe skin conditions, potentially improving recovery and quality of life for those affected.

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