Spinal fusion surgery – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:19:58 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Spinal fusion surgery – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Comparing Ropivacaine with Epinephrine Injection Methods for Pain and Bleeding Control in Patients Undergoing Lumbar Fusion Surgery https://clinicaltrials.eu/trial/comparing-ropivacaine-with-epinephrine-injection-methods-for-pain-and-bleeding-control-in-patients-undergoing-lumbar-fusion-surgery/ Wed, 29 Apr 2026 15:07:29 +0000 https://clinicaltrials.eu/trial/comparing-ropivacaine-with-epinephrine-injection-methods-for-pain-and-bleeding-control-in-patients-undergoing-lumbar-fusion-surgery/ This study focuses on comparing two different methods for controlling pain and bleeding during lumbar fusion surgery, a procedure performed on the lower back to join two or more vertebrae together. The study will evaluate two techniques: Periarticular Vasoconstrictor Infiltration (PIV) and Erector Spinae Plane Block (ESP), which are methods used to reduce blood loss and manage pain during and after surgery.

The medications used in this study include ropivacaine, a local anesthetic that helps control pain, and epinephrine, a medication that helps reduce bleeding. Both medications will be given as injections near the surgical area. The purpose of this research is to determine which of these two methods is more effective in reducing blood loss and controlling pain after spine surgery.

During the study, patients undergoing lumbar fusion surgery will receive either the PIV or ESP treatment. The medical team will monitor the amount of blood loss during surgery and track how well pain is controlled afterward. This research aims to help doctors better understand which method provides better results for patients having this type of back surgery.

]]> Study on Ropivacaine for Managing Post-Operative Pain in Patients Undergoing Lumbar Arthrodesis Surgery https://clinicaltrials.eu/trial/study-on-ropivacaine-for-managing-post-operative-pain-in-patients-undergoing-lumbar-arthrodesis-surgery/ Wed, 29 Apr 2026 15:02:07 +0000 https://clinicaltrials.eu/trial/study-on-ropivacaine-for-managing-post-operative-pain-in-patients-undergoing-lumbar-arthrodesis-surgery/ This clinical trial is focused on studying the effectiveness and safety of a medication called Ropivacaine in managing pain after surgery. Specifically, it looks at patients who have undergone a type of back surgery known as lumbar arthrodesis. The study aims to compare two methods of administering the medication: one method involves injecting it near the surgical area, known as a plane block, and the other involves injecting it directly into the surgical wound, known as wound infiltration.

The purpose of the study is to see if using Ropivacaine can help reduce the need for another pain medication, morphine, after surgery. Participants in the study will receive either the Ropivacaine injection or a placebo. The study will monitor how much morphine is needed in the 48 hours following surgery. Additionally, it will assess pain levels at various times after surgery, the quality of recovery, the length of hospital stay, and any side effects from the drug.

Participants will be observed for changes in their pain levels and overall recovery during the first two days after surgery. The study will also track any adverse effects related to the use of Ropivacaine during this period. This research aims to provide insights into better pain management strategies for patients undergoing lumbar arthrodesis surgery.

]]> Study on Pain Relief After Lumbar Spinal Surgery Using Erector Spinae Plane Block with Etoricoxib and Drug Combination for Patients Undergoing Lumbar Arthrodesis https://clinicaltrials.eu/trial/study-on-pain-relief-after-lumbar-spinal-surgery-using-erector-spinae-plane-block-with-etoricoxib-and-drug-combination-for-patients-undergoing-lumbar-arthrodesis/ Wed, 29 Apr 2026 14:26:54 +0000 https://clinicaltrials.eu/trial/study-on-pain-relief-after-lumbar-spinal-surgery-using-erector-spinae-plane-block-with-etoricoxib-and-drug-combination-for-patients-undergoing-lumbar-arthrodesis/ This clinical trial is focused on evaluating the effectiveness of a pain management technique called the erector spinae plane block in patients undergoing lumbar spinal surgery, specifically lumbar arthrodesis. Lumbar arthrodesis is a type of back surgery where two or more vertebrae in the lower back are fused together to reduce pain and improve stability. The study aims to assess whether this technique can reduce the need for pain medications, such as morphine, after surgery.

Participants in the study will receive either the erector spinae plane block or a placebo during their surgery. The block is a type of anesthesia that numbs the nerves in the back to help manage pain. The study will compare the amount of morphine needed by patients who receive the block to those who do not, over the first 24 hours after surgery. The trial will also monitor other factors such as blood pressure, heart rate, and any complications related to the block, as well as the overall quality of recovery.

In addition to morphine, other medications used in the study include etoricoxib, paracetamol, tramadol hydrochloride, methylprednisolone, propofol, lidocaine hydrochloride monohydrate, sevoflurane, sufentanil, rocuronium bromide, and levobupivacaine hydrochloride. These medications are commonly used for pain relief, anesthesia, and muscle relaxation during and after surgery. The study will help determine the best approach to managing pain and improving recovery for patients undergoing lumbar spinal surgery.

]]>