Smoking cessation therapy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:16:00 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Smoking cessation therapy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Safety and Effectiveness of Cytisinicline for Helping Smokers Quit https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-cytisinicline-for-helping-smokers-quit/ Wed, 29 Apr 2026 15:04:49 +0000 https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-cytisinicline-for-helping-smokers-quit/ This clinical trial is focused on helping people who are active smokers and want to quit smoking. The study is testing a treatment called cytisinicline, which is taken as a film-coated tablet. Cytisinicline is a chemical substance that may help people stop smoking by reducing their cravings for cigarettes.

The purpose of the study is to evaluate the safety and effectiveness of cytisinicline when used for different lengths of time. Participants will be randomly assigned to one of three groups, each receiving cytisinicline for either 25, 50, or 75 days. The study will observe how well the treatment works and how safe it is over these different periods. Participants will be monitored at various points during the study to see if they have stopped smoking and to check for any side effects.

The trial will take place over several months, with follow-up checks at 3, 6, and 12 months to assess the participants’ progress in quitting smoking. The study aims to provide valuable information on the best way to use cytisinicline to help people quit smoking safely and effectively.

]]> Study on Using Nicotine Electronic Cigarettes and Varenicline for Smoking Cessation in Smokers of 10+ Cigarettes Daily https://clinicaltrials.eu/trial/study-on-using-nicotine-electronic-cigarettes-and-varenicline-for-smoking-cessation-in-smokers-of-10-cigarettes-daily/ Wed, 29 Apr 2026 14:58:24 +0000 https://clinicaltrials.eu/trial/study-on-using-nicotine-electronic-cigarettes-and-varenicline-for-smoking-cessation-in-smokers-of-10-cigarettes-daily/ This clinical trial is focused on helping people who smoke at least 10 cigarettes a day to quit smoking. The study is comparing three different methods to assist with smoking cessation: electronic cigarettes with nicotine, electronic cigarettes without nicotine, and a medication called . Varenicline is a treatment that comes in the form of film-coated tablets and is known by the brand name . It is a licensed medication used to help people stop smoking.

The purpose of the study is to evaluate how effective electronic cigarettes containing nicotine are compared to electronic cigarettes without nicotine and to . Participants in the study will be randomly assigned to one of these three groups. The study will last for a period of three months, during which participants will be monitored to see if they can stop smoking continuously for the last four weeks of the treatment period. The study will also look at the safety of these methods by comparing any serious or non-serious side effects that may occur.

Throughout the study, researchers will also assess other factors such as the time it takes for participants to relapse into smoking after their target quit day, changes in the number of cigarettes smoked per day, cravings for tobacco, and withdrawal symptoms. The goal is to find out which method is most effective and safe for helping people quit smoking.

]]> Study on Cytisine for Quitting Nicotine E-Cigarettes and Tobacco in Motivated Individuals https://clinicaltrials.eu/trial/study-on-cytisine-for-quitting-nicotine-e-cigarettes-and-tobacco-in-motivated-individuals/ Wed, 29 Apr 2026 14:26:19 +0000 https://clinicaltrials.eu/trial/study-on-cytisine-for-quitting-nicotine-e-cigarettes-and-tobacco-in-motivated-individuals/ This clinical trial is focused on helping people quit using nicotine-containing electronic cigarettes and tobacco cigarettes. The study is testing a treatment called cytisine, which is a chemical substance used in a tablet form. Participants in the study will receive either cytisine or a placebo, which looks like the cytisine tablet but does not contain the active substance. Both groups will also receive support to help them quit smoking or vaping.

The purpose of the study is to evaluate how effective cytisine is in helping people stop using electronic cigarettes and tobacco cigarettes. Participants who are motivated to quit will be divided into two groups. One group will take cytisine tablets for 12 weeks, while the other group will take placebo tablets for the same period. Both groups will receive behavioral support to assist them in quitting. The study will monitor participants for 30 weeks to see if they can remain smoke-free and vape-free.

Throughout the study, participants will be asked to report their progress and may undergo tests to confirm they have stopped using nicotine products. The goal is to see if cytisine, combined with support, can help people quit smoking and vaping more effectively than support alone. This study aims to provide valuable information on the potential benefits of cytisine for those looking to quit nicotine use.

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