Sleep disorder – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:24:51 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Sleep disorder – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A study to evaluate the effect of sodium oxybate on sleep quality in adult patients in intensive care units https://clinicaltrials.eu/trial/a-study-to-evaluate-the-effect-of-sodium-oxybate-on-sleep-quality-in-adult-patients-in-intensive-care-units/ Thu, 30 Apr 2026 13:08:56 +0000 https://clinicaltrials.eu/trial/a-study-to-evaluate-the-effect-of-sodium-oxybate-on-sleep-quality-in-adult-patients-in-intensive-care-units/ This study focuses on adults receiving care in the intensive care unit, which is a specialized hospital department for patients with serious illnesses. Many patients in this setting experience sleep disorders, which are problems with the quality or amount of sleep. The research aims to determine if the administration of sodium oxybate (also known as GAMMA-OH) through an intravenous line, which is a needle placed into a vein, can increase the amount of deep slow-wave sleep. This specific stage of sleep is the deepest part of the sleep cycle, essential for rest and recovery.

During the study, participants may receive either GAMMA-OH or a placebo, which is a substance containing NaCl 0.9% (salt water) with no active medicine. The study uses polysomnography, a method of monitoring sleep through various sensors, to observe different sleep stages such as Rapid Eye Movement (REM) sleep and light sleep. Researchers will also look at how the treatment affects daytime alertness and the need for pain medications like morphine. Additionally, the study monitors for potential side effects, such as bradycardia, which is a slow heart rate, or changes in blood sodium levels.

]]> Study on the Effects of DHEA and Melatonin on Sleep and Mood in Postmenopausal Women with Sleep Disorders https://clinicaltrials.eu/trial/study-on-the-effects-of-dhea-and-melatonin-on-sleep-and-mood-in-postmenopausal-women-with-sleep-disorders/ Wed, 29 Apr 2026 15:03:53 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-dhea-and-melatonin-on-sleep-and-mood-in-postmenopausal-women-with-sleep-disorders/ This clinical trial is focused on studying the effects of a combination treatment on sleep quality and mood in women who have gone through menopause. Menopause is a natural phase in a woman’s life when her menstrual periods stop permanently, and she can no longer become pregnant. During this time, many women experience sleep disorders and mood changes. The treatment being studied includes two medications: DHEA (20 mg) and melatonin (2 mg), which is a prolonged-release tablet. DHEA is a hormone that the body naturally produces, and melatonin is a hormone that helps regulate sleep.

The purpose of this study is to see if taking these medications together for 12 weeks can improve sleep quality and mood in postmenopausal women. The study will also look at whether this combination can reduce daytime sleepiness and the severity of symptoms like hot flashes, which are common during menopause. Participants will be randomly assigned to receive either the medication combination or a placebo, and neither the participants nor the researchers will know who is receiving which treatment until the study is completed.

Throughout the study, participants will take the medication or placebo orally, meaning by mouth, for a period of 12 weeks. The study will monitor changes in sleep quality, mood, and menopausal symptoms. Additionally, the study will assess the effects of the treatment on certain hormone levels in the blood. This research aims to provide more information on how these medications might help improve the quality of life for women experiencing menopause-related issues.

]]> Study on Elinzanetant for Treating Sleep Disturbances in Menopausal Women https://clinicaltrials.eu/trial/study-on-elinzanetant-for-treating-sleep-disturbances-in-menopausal-women/ Wed, 29 Apr 2026 14:47:57 +0000 https://clinicaltrials.eu/trial/study-on-elinzanetant-for-treating-sleep-disturbances-in-menopausal-women-2/ This clinical trial is focused on studying sleep disturbances associated with menopause. The treatment being tested is a medication called elinzanetant, which is being compared to a placebo. The purpose of the study is to learn about how elinzanetant works and how safe it is for women experiencing sleep problems during menopause.

Participants in the study will be randomly assigned to receive either elinzanetant or a placebo. The study will last for several weeks, during which participants will take the medication in the form of a soft capsule. Throughout the study, participants will be monitored to assess any changes in their sleep patterns and overall well-being.

The study aims to explore the effectiveness of elinzanetant in improving sleep quality for women who are in the post-menopausal period. By the end of the study, researchers hope to gather valuable information on whether elinzanetant can help alleviate sleep disturbances associated with menopause.

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