Skin ulcer – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Tue, 02 Jun 2026 12:23:49 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Skin ulcer – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Stem Cell Treatment for Venous Ulcers in the Legs Using Bioengineered Artificial Mesenchymal Sheet (BAMS) https://clinicaltrials.eu/trial/study-on-stem-cell-treatment-for-venous-ulcers-in-the-legs-using-bioengineered-artificial-mesenchymal-sheet-bams/ Wed, 27 May 2026 09:46:29 +0000 https://clinicaltrials.eu/trial/study-on-stem-cell-treatment-for-venous-ulcers-in-the-legs-using-bioengineered-artificial-mesenchymal-sheet-bams/ This clinical trial is focused on studying the treatment of , a condition where wounds on the legs do not heal properly due to poor blood circulation. The treatment being tested is called , which is made from special cells known as . These cells are grown on a supportive structure called a , which helps them function like living tissue. The purpose of the study is to determine if this treatment is safe and effective for patients with venous ulcers.

Participants in the study will be randomly assigned to receive either the BAMS treatment or a placebo. The study will take place over several months, during which the healing of the ulcers will be closely monitored. Researchers will look at how well the wounds close, how the healing progresses, and any changes in pain levels. They will also assess the overall quality of life for participants after receiving the treatment.

The trial aims to provide valuable information on whether this new approach can improve healing for people with venous ulcers. By understanding the effects of BAMS, researchers hope to offer a new option for those suffering from this challenging condition.

]]> Study on the Effectiveness of EscharEx and Amnion/Chorion Membrane Allograft for Patients with Venous Leg Ulcers https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-escharex-and-amnion-chorion-membrane-allograft-for-patients-with-venous-leg-ulcers/ Wed, 29 Apr 2026 15:05:19 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-escharex-and-amnion-chorion-membrane-allograft-for-patients-with-venous-leg-ulcers/ This clinical trial is focused on studying the treatment of , which are wounds that occur on the legs due to poor blood flow in the veins. The study will evaluate the effectiveness and safety of a treatment called , which is a powder that turns into a gel when applied to the wound. This gel contains a special ingredient known as a , which helps in cleaning the wound by removing dead tissue. The study will also use a for comparison, which looks like the treatment gel but does not contain the active ingredient.

The purpose of the study is to see how well works in cleaning and preparing the wound bed for healing. Participants in the study will receive either the treatment or the placebo. The treatment will be applied directly to the wound, and the progress will be monitored over a period of time. The study will also involve the use of an , which is a patch made from human tissue, to help with the healing process. This patch is applied to the wound to support the growth of healthy tissue.

Throughout the study, the main focus will be on how effectively the treatment cleans the wound and helps it to close completely. The study will also look at how quickly the wound area changes and how soon healthy tissue forms. Participants will have regular visits to check the progress of their wound healing. The study aims to provide valuable information on the potential benefits of for people with .

]]> Study on the Effectiveness of Allo-APZ2-CVU for Patients with Long-Term, Non-Healing Venous Leg Ulcers https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-allo-apz2-cvu-for-patients-with-long-term-non-healing-venous-leg-ulcers/ Wed, 29 Apr 2026 15:03:44 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-allo-apz2-cvu-for-patients-with-long-term-non-healing-venous-leg-ulcers/ This clinical trial is focused on studying the treatment of chronic venous ulcers, which are long-lasting wounds on the legs that do not heal properly. The study will test a new treatment called allo-APZ2-CVU, which is a type of cell therapy made from special skin cells. These cells are known as allogeneic skin-derived ABCB5-positive dermal mesenchymal stromal cells. The treatment is applied directly to the skin in the form of a suspension, which is a liquid containing the cells.

The purpose of the study is to see how well this new treatment works in helping these difficult-to-heal wounds close completely and to ensure it is safe for patients. Participants in the study will receive either the new treatment or a placebo, which looks like the treatment but does not contain the active cells. The study will follow patients over a period of time to monitor the healing of their wounds and any side effects they might experience.

Throughout the study, the healing progress of the wounds will be checked regularly, and the overall quality of life of the participants will be assessed using questionnaires. The study aims to provide valuable information on whether this new cell therapy can be an effective and safe option for people suffering from chronic venous ulcers.

]]> Study on the Effectiveness and Safety of allo-APZ2-CVU for Healing Chronic Venous Ulcers in Patients with Therapy-Resistant Wounds https://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-allo-apz2-cvu-for-healing-chronic-venous-ulcers-in-patients-with-therapy-resistant-wounds/ Wed, 29 Apr 2026 14:47:59 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-allo-apz2-cvu-for-healing-chronic-venous-ulcers-in-patients-with-therapy-resistant-wounds-2/ This clinical trial is focused on studying the effects of a new treatment for chronic venous ulcers (CVU), which are long-lasting wounds that occur due to poor blood circulation in the veins of the legs. The treatment being tested is called allo-APZ2-CVU, a type of cell therapy that uses special cells derived from skin to help heal these stubborn wounds. The study will compare the effects of three different doses of this treatment to a placebo to see how well it helps in closing the wounds and ensuring safety for the patients.

The main goal of the study is to observe how effectively the treatment can close the wounds and to monitor any side effects that may occur. Participants will receive the treatment applied directly to their wounds. The study will take place over several weeks, with regular follow-up visits to check on the progress of wound healing and to assess any changes in the size of the wound, the time it takes to heal, and the quality of healing. The study will also evaluate the impact of the treatment on the participants’ quality of life and any pain they experience.

By participating in this study, researchers aim to gather valuable information on the potential benefits and safety of allo-APZ2-CVU for individuals suffering from chronic venous ulcers. This could lead to new treatment options for those who have not responded to existing therapies. The study is designed to ensure that all participants are closely monitored throughout the process to ensure their well-being and to collect accurate data on the treatment’s effectiveness.

]]> Study on Acetic Acid for Healing Skin Ulcers in Patients with Biofilm https://clinicaltrials.eu/trial/study-on-acetic-acid-for-healing-skin-ulcers-in-patients-with-biofilm/ Wed, 29 Apr 2026 14:26:31 +0000 https://clinicaltrials.eu/trial/study-on-acetic-acid-for-healing-skin-ulcers-in-patients-with-biofilm/ This clinical trial is focused on studying the treatment of skin ulcers, which are open sores that can develop on the skin. The treatment being tested is a topical solution containing acetic acid, glacial, which is applied directly to the skin. The purpose of the study is to evaluate how effective this treatment is in helping skin ulcers heal, particularly those with a layer of bacteria known as a biofilm.

Participants in the study will receive either the acetic acid treatment or a control treatment. The study will last for a period of 8 weeks, during which the change in the size of the ulcer will be monitored. The goal is to see if the acetic acid treatment can reduce the size of the ulcer more effectively than the control treatment. The study will also look at how many participants experience complete healing of their ulcers at different points during the study, such as at 4 weeks and 12 weeks.

Throughout the study, researchers will also keep track of any side effects that participants may experience from the treatment. Additionally, the study will assess the time it takes for ulcers to heal and the associated healthcare costs. This information will help determine the overall effectiveness and safety of using acetic acid for treating skin ulcers.

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