Skin graft – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 10:51:12 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Skin graft – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Safety and Effectiveness of EHSG-KF for Treating Full-Thickness Skin Defects in Adults and Children https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-ehsg-kf-for-treating-full-thickness-skin-defects-in-adults-and-children/ Wed, 29 Apr 2026 14:22:37 +0000 https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-ehsg-kf-for-treating-full-thickness-skin-defects-in-adults-and-children/ This clinical trial is focused on studying a new treatment for people with full-thickness skin defects, which are deep wounds that affect all layers of the skin. These defects can occur in both adults and children due to various reasons such as scars, benign skin tumors, or injuries. The treatment being tested is called EHSG-KF, a special type of skin graft made from a bilayer engineered collagen hydrogel that includes the patient’s own skin cells, specifically keratinocytes and fibroblasts. This new treatment will be compared to the traditional method of using autologous split-thickness skin grafts (STSG), which involves taking a thin layer of skin from another part of the patient’s body.

The purpose of the study is to evaluate how effective and safe the EHSG-KF treatment is compared to the traditional STSG method. Participants in the study will receive both types of skin grafts, and the healing process will be monitored over time. The study will look at various aspects of healing, such as the quality of the scar, using tools like the POSAS questionnaire, which helps assess the appearance and feel of the scar. The study will also check for any signs of infection and other side effects throughout the healing process.

Participants will be followed for a period of time to see how well the skin heals and to compare the results of the new treatment with the traditional method. The study aims to provide valuable information on whether the EHSG-KF treatment can offer a better or safer option for treating deep skin wounds. This research could potentially lead to improved outcomes for patients with significant skin defects.

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