Sinusitis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Tue, 02 Jun 2026 04:15:11 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Sinusitis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of Actisoufre nasal spray containing sodium sulfide and saccharomyces extract for adults and children over 6 years with acute rhinitis, rhinopharyngitis, and rhinosinusitis https://clinicaltrials.eu/trial/study-of-actisoufre-nasal-spray-containing-sodium-sulfide-and-saccharomyces-extract-for-adults-and-children-over-6-years-with-acute-rhinitis-rhinopharyngitis-and-rhinosinusitis/ Wed, 29 Apr 2026 15:06:23 +0000 https://clinicaltrials.eu/trial/study-of-actisoufre-nasal-spray-containing-sodium-sulfide-and-saccharomyces-extract-for-adults-and-children-over-6-years-with-acute-rhinitis-rhinopharyngitis-and-rhinosinusitis/ This study examines the effectiveness of Actisoufre nasal spray in treating acute rhinitis (inflammation of the nasal passages), rhinopharyngitis (inflammation of the nose and throat area), and rhinosinusitis (inflammation of the nose and sinuses) that do not require antibiotic treatment. The study will test whether the nasal spray containing sodium sulfide nonahydrate and Saccharomyces cerevisiae extract can help reduce symptoms like nasal congestion, runny nose, and thick mucus.

The purpose of this research is to evaluate how well Actisoufre nasal spray works compared to placebo when used three times daily in each nostril for seven days. The study involves both adults and children over 6 years old who have developed sudden symptoms of nose and throat inflammation within the previous 48 hours.

During the study, participants will use either Actisoufre nasal spray or placebo. They will need to report their symptoms, including how well they sleep and their overall quality of life. The researchers will track any changes in symptoms, particularly focusing on improvements in nasal congestion, runny nose, and other related symptoms over the course of treatment.

]]> Study on Oral Prednisolone and Sucrose for Treating Wheezing Caused by Rhinovirus in Children Under 2 Years Old https://clinicaltrials.eu/trial/study-on-oral-prednisolone-and-sucrose-for-treating-wheezing-caused-by-rhinovirus-in-children-under-2-years-old/ Wed, 29 Apr 2026 14:30:17 +0000 https://clinicaltrials.eu/trial/study-on-oral-prednisolone-and-sucrose-for-treating-wheezing-caused-by-rhinovirus-in-children-under-2-years-old/ This clinical trial is focused on studying children under 2 years old who experience wheezing caused by a common cold virus known as the rhinovirus. Wheezing is a high-pitched whistling sound made while breathing, often associated with difficulty in breathing. The study aims to determine if a medication called prednisolone sodium phosphate, which is a type of steroid that helps reduce inflammation, can help these children. The treatment involves taking the medication orally, which means it is swallowed in the form of a liquid solution.

During the study, children will receive either the prednisolone sodium phosphate or a placebo, which is a substance with no active medication. The study will last for a short period, and the children will be monitored to see how quickly they recover from wheezing and if they need to stay in the hospital for a shorter time. The goal is to see if the medication helps them get better faster and reduces the need for additional medical care.

Parents and caregivers will be informed about the progress and any changes in the child’s condition throughout the study. The study will also track if the children experience any recurrence of wheezing or other related symptoms over a period of time after the initial treatment. This research is important to find better ways to help young children who suffer from wheezing due to viral infections.

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