Resuscitation – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Mon, 03 Aug 2026 10:36:21 +0000 en-US hourly 1 https://wordpress.org/?v=7.1 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Resuscitation – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of anti-seizure drug combination in comatose patients with status epilepticus after cardiac arrest https://clinicaltrials.eu/trial/study-on-anti-seizure-treatment-with-esketamine-lorazepam-and-midazolam-for-comatose-patients-after-cardiac-arrest-with-status-epilepticus/ Mon, 03 Aug 2026 10:36:21 +0000 https://clinicaltrials.eu/trial/study-on-anti-seizure-treatment-with-esketamine-lorazepam-and-midazolam-for-comatose-patients-after-cardiac-arrest-with-status-epilepticus/ This study focuses on patients who experience status epilepticus (a severe form of continuous seizures) after cardiac arrest and cardiopulmonary resuscitation. The study aims to determine if treating seizures with medications improves recovery in unconscious patients who have survived cardiac arrest.

The study uses several anti-seizure medications administered through a vein, including diazepam, midazolam, lorazepam, propofol, esketamine, lacosamide, levetiracetam, and sodium valproate. These medications are given in a step-by-step approach to stop the seizure activity that is detected by brain wave monitoring.

The research will compare patients who receive seizure treatment with those who do not receive treatment. The main focus is on how well patients recover their ability to function in daily life six months after their cardiac arrest. The study will also look at the cost-effectiveness of the treatment approach.

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