Pregnancy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:16:43 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Pregnancy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Best Timing for Pertussis Vaccination in Pregnant Women Using Diphtheria, Tetanus, and Pertussis Vaccine https://clinicaltrials.eu/trial/study-on-the-best-timing-for-pertussis-vaccination-in-pregnant-women-using-diphtheria-tetanus-and-pertussis-vaccine/ Wed, 29 Apr 2026 15:05:34 +0000 https://clinicaltrials.eu/trial/study-on-the-best-timing-for-pertussis-vaccination-in-pregnant-women-using-diphtheria-tetanus-and-pertussis-vaccine/ This clinical trial is focused on understanding the best time to give the pertussis vaccine to pregnant women. Pertussis, also known as whooping cough, is a contagious disease that can be serious for babies. The vaccine being studied is called Triaxis, which is a combination vaccine that protects against diphtheria, tetanus, and pertussis. The study aims to see how the timing of the vaccine during pregnancy affects the immune system of the mother and the baby.

The purpose of the study is to assess how the timing of the Tdap vaccine (which stands for tetanus, diphtheria, and acellular pertussis) during pregnancy influences the immune responses in pregnant women. This includes looking at the levels of antibodies, which are proteins in the blood that help fight infections, in the mother’s blood at different times: before the vaccine, after the vaccine, at the time of delivery, and six months after giving birth. The study will also measure the levels of antibodies in the baby’s blood at birth to understand how well these protective proteins are passed from the mother to the baby through the placenta.

Participants in the study will receive the Tdap vaccine during their pregnancy. The study will involve several visits to monitor the immune responses, including blood tests to measure antibody levels and other immune markers. The study will also look at the presence of antibodies in breast milk six months after giving birth to see how the vaccine timing affects the baby’s protection after birth. This research will help determine the best time to vaccinate pregnant women to provide the most protection for both the mother and the baby.

]]> Study on Antibiotic Levels in Blood of Pregnant Women with Twins Using Piperacillin, Tazobactam, Cefazolin, Ampicillin Sodium, and Clindamycin https://clinicaltrials.eu/trial/study-on-antibiotic-levels-in-blood-of-pregnant-women-with-twins-using-piperacillin-tazobactam-cefazolin-ampicillin-sodium-and-clindamycin/ Wed, 29 Apr 2026 15:02:29 +0000 https://clinicaltrials.eu/trial/study-on-antibiotic-levels-in-blood-of-pregnant-women-with-twins-using-piperacillin-tazobactam-cefazolin-ampicillin-sodium-and-clindamycin/ This clinical trial focuses on understanding how antibiotics work in women who are pregnant with twins. The study involves several antibiotics, including piperacillin, tazobactam, cefazolin, ampicillin sodium, and clindamycin. These medications are commonly used to treat infections and will be given through a vein, known as intravenous use. The purpose of the study is to determine the concentration of these antibiotics in the blood of the mother and the newborns, specifically looking at any differences between the twin siblings.

Participants in the study will be women with twin pregnancies who are having a cesarean section, which is a surgical procedure to deliver the babies. The study will measure the levels of antibiotics in the mother’s blood and the blood from the umbilical cord, which connects the mother to the babies. This will help researchers understand how the antibiotics are distributed in the body and how they might affect the twins differently. The study will also look at the safety and any side effects of the antibiotics used.

The trial aims to provide valuable information about the use of antibiotics during twin pregnancies, which can help improve treatment and care for both mothers and their babies. By studying the differences in antibiotic levels between the twins, researchers hope to gain insights into how these medications work in such unique pregnancies. The study is expected to continue until 2025, gathering data to ensure the safety and effectiveness of these treatments.

]]>