Postoperative care – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Wed, 24 Jun 2026 04:15:24 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Postoperative care – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effect of Continuous Intravenous Lidocaine and Sodium Chloride on Comfort in Postoperative Critical Care Patients https://clinicaltrials.eu/trial/study-on-the-effect-of-continuous-intravenous-lidocaine-and-sodium-chloride-on-comfort-in-postoperative-critical-care-patients/ Wed, 29 Apr 2026 15:06:05 +0000 https://clinicaltrials.eu/trial/study-on-the-effect-of-continuous-intravenous-lidocaine-and-sodium-chloride-on-comfort-in-postoperative-critical-care-patients/ This clinical trial is focused on patients who are in postoperative critical care, which means they are receiving intensive medical attention after undergoing major surgery. The study is investigating the effects of a medication called lidocaine hydrochloride monohydrate, which is commonly used as a local anesthetic to numb tissue in a specific area. In this trial, it is being administered continuously through an intravenous (IV) line to see if it can help improve the comfort of patients during their stay in the intensive care unit.

The purpose of the study is to determine whether the continuous administration of lidocaine during the first 48 hours after surgery can enhance patients’ comfort levels. Patients will receive either the lidocaine treatment or a placebo for comparison. The study will monitor patients’ comfort using a questionnaire that assesses various aspects of discomfort, such as noise, thirst, pain, and anxiety, among others. The trial will also track other factors like the use of pain medication, the duration of mechanical ventilation, and the length of stay in critical care.

Participants in the study will be closely observed for any side effects related to the use of lidocaine. The trial aims to provide valuable insights into whether this treatment can make a significant difference in the recovery experience of patients in critical care after major surgeries. The study is expected to continue until 2027, with recruitment starting in 2025.

]]> Study of Dexmedetomidine Effects on Sleep Quality and Fatigue After Major Surgery in Elderly Patients Aged 60 and Older https://clinicaltrials.eu/trial/study-on-the-effect-of-dexmedetomidine-on-sleep-quality-and-fatigue-after-major-surgery-in-patients-aged-60-and-older/ Wed, 29 Apr 2026 14:30:34 +0000 https://clinicaltrials.eu/trial/study-on-the-effect-of-dexmedetomidine-on-sleep-quality-and-fatigue-after-major-surgery-in-patients-aged-60-and-older/ This study focuses on elderly patients aged 60 and above who undergo thoracoscopic lung resection surgery. The research examines how dexmedetomidine, given during the first night after surgery, affects sleep quality and recovery. This medication is administered through intravenous infusion along with sodium chloride solution.

The main purpose of this research is to determine if using dexmedetomidine at night after major surgery can improve sleep quality and reduce post-surgery tiredness and muscle weakness. The medication will be given as an infusion through a vein during the first night following the operation.

During the study, researchers will monitor various aspects of recovery including sleep patterns, physical strength, tiredness levels, and overall well-being. They will use different questionnaires and tests to measure how well patients recover after their surgery. The study will also look at brain activity during sleep and track various body chemicals that indicate how well the body is healing after surgery.

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