Post procedural swelling – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:29:37 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Post procedural swelling – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effects of Horse Chestnut Seed Extract on Swelling and Pain in Patients After Meniscus Surgery https://clinicaltrials.eu/trial/study-on-the-effects-of-horse-chestnut-seed-extract-on-swelling-and-pain-in-patients-after-meniscus-surgery/ Wed, 29 Apr 2026 14:24:50 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-horse-chestnut-seed-extract-on-swelling-and-pain-in-patients-after-meniscus-surgery/ This clinical trial is focused on studying the effects of a treatment for post-operative swelling, pain, and edema in patients who have undergone meniscus surgery. The treatment being tested is a medication called Aescuven, which contains a dry extract of horse chestnut. This extract is standardized to contain a specific amount of active compounds known as triterpene glycosides. The study will compare the effects of Aescuven to a placebo, which looks and tastes like the real medication but contains no active ingredients.

The purpose of the study is to determine if Aescuven can effectively reduce swelling, pain, and fluid buildup after meniscus surgery. Participants in the study will take four tablets of Aescuven daily, divided into two doses. The study will be conducted in a way that neither the participants nor the researchers know who is receiving the actual medication or the placebo, ensuring unbiased results. This type of study is known as a double-blind trial.

Throughout the study, participants will have several visits where their knee’s condition will be assessed. These assessments will include measuring the knee’s volume and circumference, checking the range of motion, and evaluating the skin temperature at the surgery site. The study will also track the amount of pain medication used by participants and their overall quality of life during the trial period. The study aims to provide valuable information on the potential benefits of using Aescuven for managing post-surgical symptoms in meniscus surgery patients.

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