Post breast therapy pain syndrome – European Clinical Trials Information Network

Study Comparing Serratus Plane Block, Capsaicin, and Botulinum Toxin Type A for Chronic Pain in Post-Mastectomy Patients

Wed, 29 Apr 2026 15:03:02 +0000

This clinical trial is focused on finding effective treatments for chronic neuropathic pain that occurs after a mastectomy, which is a surgery to remove one or both breasts, usually to treat breast cancer. The study is comparing three different treatments: a Serratus Plane Block (SPB), an 8% capsaicin patch, and Botulinum toxin type A. The purpose of the study is to evaluate how well these treatments can control pain that persists after initial treatments have not been successful.

Participants in the study will receive one of the three treatments and will be monitored over a period of time to assess the effectiveness of the treatment in reducing pain. The main assessment will take place 8 weeks after the treatment begins. During the study, participants will be asked to rate their pain levels using a simple scale from 0 to 10, where 0 means no pain and 10 means the worst pain imaginable. This self-assessment helps to understand how the treatment is working from the participant’s perspective.

Throughout the study, additional evaluations will be conducted at various intervals to track changes in pain levels and any side effects that may occur. The study aims to provide valuable information on which treatment might be most effective for managing chronic pain after a mastectomy, offering hope for better pain management options in the future.

Study on Botulinum Toxin Type A and Capsaicin for Treating Postmastectomy Pain in Women After Breast Cancer Surgery

Wed, 29 Apr 2026 14:59:52 +0000

This clinical trial is focused on studying the treatment of Postmastectomy Syndrome, a condition that can cause moderate to severe pain in women who have undergone surgery for breast cancer. The study will compare two treatments: Botulinum Toxin type A, also known by its code name NT 201, and topical Capsaicin. Botulinum Toxin type A is a solution for injection, while Capsaicin is applied as a cutaneous patch on the skin.

The purpose of the study is to determine how effective these treatments are in managing pain associated with Postmastectomy Syndrome. Participants will be randomly assigned to receive either Botulinum Toxin type A or Capsaicin. The study will be conducted in a way that neither the participants nor the researchers know which treatment is being administered, ensuring unbiased results. The trial will involve regular assessments of pain intensity and the type of pain experienced, such as burning or stabbing sensations.

Throughout the study, any side effects will be recorded, along with the level of satisfaction participants feel with their treatment. The use of any additional pain relief medications will also be monitored. This trial aims to provide valuable insights into the management of pain for women suffering from Postmastectomy Syndrome following breast cancer surgery.