Pertussis immunisation – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:28:25 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Pertussis immunisation – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effectiveness of dTap Vaccine in Boosting Immunity Against Diphtheria, Tetanus, and Whooping Cough in Healthcare Workers https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-dtap-vaccine-in-boosting-immunity-against-diphtheria-tetanus-and-whooping-cough-in-healthcare-workers/ Wed, 29 Apr 2026 15:05:49 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-dtap-vaccine-in-boosting-immunity-against-diphtheria-tetanus-and-whooping-cough-in-healthcare-workers/ This clinical trial is focused on studying the immune response to a booster vaccination in healthcare workers. The diseases being studied are diphtheria, tetanus, and pertussis (commonly known as whooping cough). The treatment used in this study is a vaccine called dTap, which is designed to boost immunity against these diseases. The vaccine contains several components, including diphtheria toxoid, tetanus toxoid, and various parts of the pertussis bacteria that help the body recognize and fight the infection.

The purpose of the study is to understand how the immune system of healthcare workers responds to the dTap booster vaccine. Participants will receive the vaccine and their immune response will be measured before and after vaccination. The study will involve two visits where participants will complete questionnaires and provide blood samples. These samples will help researchers measure the levels of specific antibodies, which are proteins made by the immune system to fight infections, and other immune responses.

The study will track changes in the immune system over a period of four weeks after the booster vaccination. This includes measuring the levels of antibodies specific to pertussis, as well as the immune response to diphtheria and tetanus. The results will help determine how well the vaccine works in boosting immunity among healthcare workers who are regularly in contact with infants, a group particularly vulnerable to these diseases.

]]> Study of Long-term Pertussis Immunity in Children at Age 4 Years Following Maternal Vaccination During Pregnancy https://clinicaltrials.eu/trial/study-on-the-effects-of-maternal-vaccination-with-pertussis-toxoid-and-drug-combination-on-childrens-immunity-to-pertussis-at-4-years-old/ Wed, 29 Apr 2026 15:05:48 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-maternal-vaccination-with-pertussis-toxoid-and-drug-combination-on-childrens-immunity-to-pertussis-at-4-years-old/ This clinical trial focuses on studying pertussis, also known as whooping cough, a highly contagious respiratory infection. The study aims to examine long-term differences in immunity against pertussis in children whose mothers received vaccination during pregnancy compared to those whose mothers did not.

The study involves the use of Tetravac, which is an injectable vaccine suspension that contains inactivated components to protect against multiple diseases. This combination vaccine includes protection against diphtheria, tetanus, pertussis (whooping cough), and polio. The vaccine is given as a single injection into the muscle.

The research will follow children until they reach 4 years of age, focusing on measuring their immunity levels against pertussis. The study will involve children who previously participated in an earlier phase of research when they were 6 months old. Each participant will receive a single dose of 0.5 milliliters of the vaccine.

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