Persistent depressive disorder – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:29:37 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Persistent depressive disorder – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Long-term Use of Pramipexole for Patients with Anhedonic Depression https://clinicaltrials.eu/trial/study-on-the-long-term-use-of-pramipexole-for-patients-with-anhedonic-depression/ Wed, 29 Apr 2026 14:24:51 +0000 https://clinicaltrials.eu/trial/study-on-the-long-term-use-of-pramipexole-for-patients-with-anhedonic-depression/ This clinical trial is focused on studying the effects of the medication pramipexole in individuals with depression, specifically targeting those who experience a lack of pleasure or interest in activities, known as anhedonia. Pramipexole is a medication that comes in the form of a prolonged-release tablet, which means it is designed to release the active ingredient slowly over time when taken orally. The purpose of this study is to explore how effective and tolerable pramipexole is when used over a long period as an additional treatment for anhedonic depression.

Participants in this study will have previously taken part in a related research study that compared the short-term effects of pramipexole with a placebo. Those who were initially given pramipexole and wish to continue their treatment, as well as those who received a placebo and meet certain criteria, can join this follow-up study. The study will last for a maximum of 25 weeks, during which participants will continue to take pramipexole and be monitored for its effects on their symptoms of depression.

Throughout the study, various aspects of the participants’ health and well-being will be assessed, including their overall mood, physical activity levels, sleep patterns, and any side effects they may experience. The study aims to gather comprehensive data to better understand how pramipexole can help improve symptoms of anhedonic depression and to ensure that it is a safe and effective treatment option for long-term use.

]]>