Periodontitis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 10:53:42 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Periodontitis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effects of Vitamin D3 in Patients with Periodontitis and Vitamin D Deficiency https://clinicaltrials.eu/trial/study-on-the-effects-of-vitamin-d3-in-patients-with-periodontitis-and-vitamin-d-deficiency/ Wed, 29 Apr 2026 14:25:50 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-vitamin-d3-in-patients-with-periodontitis-and-vitamin-d-deficiency/ This clinical trial is focused on studying the effects of vitamin D3 supplementation in individuals with periodontitis and a deficiency in vitamin D. Periodontitis is a serious gum infection that damages the soft tissue and, without treatment, can destroy the bone that supports your teeth. The treatment being tested is a supplement called vitamin D3, also known as colecalciferol, which is a form of vitamin D that helps the body absorb calcium and maintain bone health. Participants in the study will receive either the vitamin D3 supplement or a placebo, which is a substance with no active therapeutic effect.

The purpose of the study is to evaluate how effective vitamin D3 is when used alongside standard non-surgical treatments for periodontitis. The study will last for 24 weeks, during which participants will take the supplement or placebo orally in the form of hard capsules. Throughout the study, participants will have regular check-ups to monitor their gum health and vitamin D levels. The main focus will be on changes in the depth of gum pockets, which are spaces that can form between the teeth and gums due to periodontitis.

By the end of the study, researchers aim to determine if vitamin D3 can help improve gum health in people with periodontitis and vitamin D deficiency. This could potentially lead to better treatment options for managing this common dental condition. Participants will be closely monitored for any side effects or changes in their health during the trial period.

]]> Study on Valaciclovir for Treating Advanced Gum Disease in Adults https://clinicaltrials.eu/trial/study-on-valaciclovir-for-treating-advanced-gum-disease-in-adults/ Wed, 29 Apr 2026 14:24:15 +0000 https://clinicaltrials.eu/trial/study-on-valaciclovir-for-treating-advanced-gum-disease-in-adults/ This clinical trial is focused on studying the effects of an antiviral drug called Valaciclovir in treating a condition known as generalized periodontitis. Generalized periodontitis is a serious gum disease that affects the tissues surrounding the teeth, leading to inflammation and potential tooth loss. The study aims to compare the effectiveness of Valaciclovir combined with standard non-surgical treatments, such as scaling and root surfacing, against the same standard treatments with a placebo. The goal is to determine if adding Valaciclovir can improve treatment outcomes for patients with this gum disease.

Participants in the study will receive either the antiviral drug Valaciclovir or a placebo, along with conventional treatments for their gum disease. The study will last for a period of 28 days, during which the effects of the treatments will be closely monitored. After the treatment period, there will be a follow-up visit two months later to evaluate the condition of the gums and the overall effectiveness of the treatment. This evaluation will help determine if the addition of Valaciclovir provides any significant benefits over the standard treatment alone.

The study is designed to be prospective, randomized, and double-blind, meaning that neither the participants nor the researchers will know who is receiving the actual drug or the placebo during the trial. This approach helps ensure that the results are unbiased and reliable. The findings from this study could potentially lead to improved treatment strategies for individuals suffering from generalized periodontitis, offering them better management of their condition and possibly preventing further complications.

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