Periarthritis – European Clinical Trials Information Network

Lidocaine Hydrochloride, Sodium Chloride, and Betamethasone Injections for Adults with Adhesive Capsulitis: A Pilot Efficacy Study

Fri, 05 Jun 2026 10:55:58 +0000

The study focuses on adhesive capsulitis, a condition that makes the shoulder joint stiff and painful, limiting everyday activities. Two treatment approaches are being compared: one uses an intra‑articular glenohumeral injection combined with a suprascapular nerve block that contains lidocaine hydrochloride, while the other uses an injection of the steroid medication betamethasone together with a placebo block made of saline solution.

The purpose of the trial is to determine which method provides better shoulder function after three months. Participants receive a single injection session and are then asked to return for check‑ups at one month, three months, six months, and twelve months, during which their shoulder movement, pain level, and ability to resume normal activities are recorded.

Study on Frozen Shoulder: Evaluating the Effectiveness of Physiotherapy, Triamcinolone Acetonide, and Lidocaine in Improving Shoulder Function and Reducing Pain

Wed, 29 Apr 2026 15:05:13 +0000

This clinical trial focuses on a condition known as frozen shoulder, which causes pain and stiffness in the shoulder joint. The study aims to explore the effectiveness of different treatments to improve shoulder function and reduce pain. The treatments being studied include physiotherapy, which involves exercises and physical methods to improve movement, and intra-articular corticosteroid injections, which are injections given directly into the joint to reduce inflammation and pain. The corticosteroid used in this study is triamcinolone acetonide, a type of medication that helps reduce swelling and pain. Additionally, a combination of physiotherapy and corticosteroid injections will be evaluated.

Another treatment being tested involves a mixture of cetrimide and lidocaine. Cetrimide is an antiseptic, and lidocaine is a local anesthetic that numbs the area to relieve pain. These treatments are administered through an injection directly into the shoulder joint. The purpose of the study is to compare how well these treatments work individually and in combination over a period of three months.

Participants in the study will receive one of the treatments and will be monitored for changes in shoulder pain and function. The study will assess improvements using various measures, including the Shoulder Pain and Disability Index, which evaluates the impact of shoulder pain on daily activities. The goal is to determine which treatment or combination of treatments provides the best relief for individuals with frozen shoulder.

Study on Pain Relief for Frozen Shoulder Using Methylprednisolone Acetate and Ropivacaine Hydrochloride in Adults

Wed, 29 Apr 2026 14:59:28 +0000

This clinical trial is focused on treating a condition known as Frozen Shoulder, also referred to as Adhesive Capsulitis. This condition is characterized by pain and stiffness in the shoulder, which can limit movement. The study will explore the effectiveness of two treatments: an injection of a medication called Depo-Medrol, which contains methylprednisolone acetate, and a procedure known as a Suprascapular Nerve Block (SSNB). The trial will compare the effects of these treatments on pain relief and shoulder function.

The purpose of the study is to determine if there is a difference in pain relief and shoulder function when patients receive a combination of a Gleno-Humeral Intra-Articular Corticosteroid Injection (GH IACI) with a SSNB compared to a GH IACI with a sham (inactive) SSNB. Additionally, the study aims to identify which patients benefit most from these treatments. Participants will receive either the active treatment or a placebo, and their progress will be monitored over a period of time to assess changes in shoulder-related disability.

Throughout the study, participants will undergo various assessments, including clinical examinations and possibly MRI scans, to evaluate the condition of their shoulder. The study will help determine the best diagnostic criteria for early-stage Frozen Shoulder and guide clinical practice in treating this condition. The results will be used to improve treatment strategies and resource allocation for patients with Frozen Shoulder.