Paresis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 19 Jun 2026 04:02:58 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Paresis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effectiveness and Safety of NT 201 (Botulinum Toxin) for Treating Lower Limb Spasticity in Adults After Stroke or Traumatic Brain Injury https://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-nt-201-botulinum-toxin-for-treating-lower-limb-spasticity-in-adults-after-stroke-or-traumatic-brain-injury/ Wed, 29 Apr 2026 15:01:05 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-nt-201-botulinum-toxin-for-treating-lower-limb-spasticity-in-adults-after-stroke-or-traumatic-brain-injury/ This clinical trial is focused on studying the effects of a treatment called NT 201, also known as botulinum toxin, on a condition called lower limb spasticity. Lower limb spasticity is a condition where muscles in the legs become stiff and difficult to move, often occurring after a stroke or traumatic brain injury. The study aims to compare the effectiveness and safety of NT 201 with a placebo in treating this condition.

Participants in the study will receive injections of NT 201 or a placebo into the muscles of the lower limbs. The treatment period will last for up to 92 days. The study will monitor changes in muscle stiffness and any side effects that may occur. The goal is to determine if NT 201 can help reduce muscle stiffness and improve movement in the affected limbs.

The study will also include an open-label extension phase, where all participants may receive NT 201, with or without additional treatment for the upper limbs. This phase will help gather more information on the long-term effects and safety of the treatment. The study is designed to provide valuable insights into the potential benefits of NT 201 for individuals with lower limb spasticity due to stroke or traumatic brain injury.

]]>