Pain in jaw – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 10:55:39 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Pain in jaw – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effects of Botulinum Toxin in Patients with Jaw Muscle Pain (TMD) https://clinicaltrials.eu/trial/study-on-the-effects-of-botulinum-toxin-in-patients-with-jaw-muscle-pain-tmd/ Wed, 29 Apr 2026 14:28:08 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-botulinum-toxin-in-patients-with-jaw-muscle-pain-tmd/ This clinical trial is focused on studying the effects of a treatment for a condition known as myogenous temporomandibular disorders (TMD), which is a type of jaw muscle pain. The treatment being tested is botulinum toxin, commonly known for its use in reducing muscle tension. The purpose of the study is to explore how this treatment might change certain biological markers in the jaw muscles of patients with TMD.

Participants in the study will receive an injection of botulinum toxin directly into the jaw muscle. This is done to see if it can help reduce the pain and alter specific biological processes in the muscle. The study will also involve a comparison with a placebo to understand the true effects of the treatment. The treatment period is relatively short, lasting only a few days, and involves a single injection.

The study aims to observe changes in the jaw muscle’s biological markers and pain levels after the treatment. These markers include gene expressions and other cellular changes that might be influenced by the botulinum toxin. The results will help determine if this treatment can effectively reduce jaw muscle pain and provide insights into the underlying mechanisms of TMD.

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