Pain in extremity – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:16:47 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Pain in extremity – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of ropivacaine, sodium chloride and gadoteric acid in nerve blocks for hip pain in healthy volunteers https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-ropivacaine-hydrochloride-sodium-chloride-and-gadoteric-acid-for-hip-pain-relief-in-healthy-volunteers/ Wed, 29 Apr 2026 15:05:39 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-ropivacaine-hydrochloride-sodium-chloride-and-gadoteric-acid-for-hip-pain-relief-in-healthy-volunteers/ This study focuses on investigating nerve blocks for hip pain management. The research compares two different types of nerve blocks: the subpectineal obturator nerve blockade (SOB) and suprainguinal fascia iliaca compartment block (SIFICB). These procedures involve injecting medications near specific nerves to provide pain relief in the hip area.

The medications used in this study include Ropivacaine, which is a local anesthetic solution for injection, and Dotarem, a contrast agent used for imaging. Sodium chloride solution is also used during the procedure. The purpose of the study is to determine how effectively these nerve blocks can reduce sensation in specific nerves, particularly the obturator nerve.

During the study, participants will receive nerve blocks and undergo various tests to measure the effectiveness of the treatment. These tests include muscle strength measurements and special imaging called MRI to see how the medication spreads in the body. The study will evaluate how well the nerve blocks work by measuring changes in muscle activity and areas of numbness in the skin.

]]> Study on Managing Moderate to Severe Limb Trauma Pain in Emergency Patients Using Sublingual Sufentanil Compared to a Drug Combination https://clinicaltrials.eu/trial/study-on-managing-moderate-to-severe-limb-trauma-pain-in-emergency-patients-using-sublingual-sufentanil-compared-to-a-drug-combination/ Wed, 29 Apr 2026 15:03:06 +0000 https://clinicaltrials.eu/trial/study-on-managing-moderate-to-severe-limb-trauma-pain-in-emergency-patients-using-sublingual-sufentanil-compared-to-a-drug-combination/ This clinical trial is focused on managing moderate to severe pain caused by a single injury to the arm or leg. The study will use a medication called sufentanil, which is administered as a sublingual tablet, meaning it is placed under the tongue to dissolve. The purpose of the study is to determine how effective this method is in relieving pain compared to the standard treatments currently used in emergency situations.

Participants in the study will receive sufentanil and their pain levels will be monitored over a period of time. The study will observe changes in pain levels at various intervals, such as 15, 30, 45, 60, 120, and 180 minutes after taking the medication. Additionally, the study will monitor for any side effects, including low blood pressure, slow heart rate, breathing difficulties, sweating, drowsiness, nausea, vomiting, and dizziness. At the end of the study, participants will be asked to rate their satisfaction with the pain management they received.

Other medications involved in the study include ketoprofen, morphine hydrochloride, paracetamol, codeine phosphate hemihydrate, tramadol hydrochloride, nefopam, and a combination of nitrous oxide and oxygen. These medications are part of the standard pain management options and will be used to compare the effectiveness of sufentanil. The study aims to provide valuable insights into the best practices for managing pain in emergency settings.

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