Otitis media chronic – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Mon, 03 Aug 2026 10:45:29 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.4 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Otitis media chronic – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of Topical Chloramphenicol vs Topical Ciprofloxacin for Treating Otorrhea in Adults with Chronic Suppurative Otitis Media https://clinicaltrials.eu/trial/non-inferiority-trial-of-topical-chloramphenicol-versus-ciprofloxacin-for-treating-otorrhea-in-adults-with-chronic-suppurative-otitis-media/ Mon, 03 Aug 2026 10:45:29 +0000 https://clinicaltrials.eu/trial/non-inferiority-trial-of-topical-chloramphenicol-versus-ciprofloxacin-for-treating-otorrhea-in-adults-with-chronic-suppurative-otitis-media/ Chronic suppurative otitis media is a long‑lasting infection of the middle ear that often causes continuous ear discharge (otorrhea) and can affect hearing. The study compares two types of ear drops: one containing chloramphenicol and the other containing ciprofloxacin. Both medications are applied directly into the ear to treat the infection.

The purpose of the study is to find out whether the chloramphenicol drops work at least as well as the ciprofloxacin drops in stopping ear discharge in adults with this condition. Participants will use the assigned ear drops for about two weeks. Doctors will examine the ear using a light‑based tool (otoscopy) and take pictures to see if the discharge has cleared. Hearing will be checked with a simple beep test (pure‑tone audiometry) at the start and after the treatment period. Throughout the study, participants will note any irritation, pain, or other side effects and answer questions about how they feel and how satisfied they are with the treatment.

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