Osteomyelitis acute – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:34:52 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Osteomyelitis acute – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Treating Acute Osteomyelitis in Children with Amoxicillin and Cloxacillin Compared to Standard Hospital Care https://clinicaltrials.eu/trial/study-on-treating-acute-osteomyelitis-in-children-with-amoxicillin-and-cloxacillin-compared-to-standard-hospital-care/ Wed, 29 Apr 2026 14:57:45 +0000 https://clinicaltrials.eu/trial/study-on-treating-acute-osteomyelitis-in-children-with-amoxicillin-and-cloxacillin-compared-to-standard-hospital-care/ This clinical trial focuses on children with acute osteomyelitis, a bone infection that is not severe. The study aims to compare two different treatment strategies. One strategy involves managing the condition at home with oral antibiotics, while the other involves traditional hospital care with antibiotics given through a vein, known as intravenous therapy. The main goal is to see if the home treatment is just as effective as the hospital treatment in ensuring complete recovery without the infection returning after six months.

The medications being studied include amoxicillin, cloxacillin, clavulanic acid, and cefazolin. Amoxicillin is used in two forms: as a powder for oral suspension and as an injection. Cloxacillin and cefazolin are given as injections, while clavulanic acid is taken orally as a powder mixed with liquid. These medications are all antibiotics, which are drugs used to treat infections caused by bacteria.

During the study, children will receive either the oral antibiotics at home or the intravenous antibiotics in the hospital. The study will monitor the children’s recovery over a period of six months to ensure there are no signs of the infection returning or any complications. The study will help determine if treating children with acute osteomyelitis at home is as safe and effective as the traditional hospital treatment.

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