Neuromuscular scoliosis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:34:59 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Neuromuscular scoliosis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Human Plasma Protein vs. Crystalloid for Fluid Management in Children with Scoliosis Undergoing Spinal Fusion Surgery https://clinicaltrials.eu/trial/study-on-human-plasma-protein-vs-crystalloid-for-fluid-management-in-children-with-scoliosis-undergoing-spinal-fusion-surgery/ Wed, 29 Apr 2026 14:57:56 +0000 https://clinicaltrials.eu/trial/study-on-human-plasma-protein-vs-crystalloid-for-fluid-management-in-children-with-scoliosis-undergoing-spinal-fusion-surgery/ This clinical trial is focused on studying the management of fluids in children who are undergoing surgery for scoliosis, a condition where the spine curves sideways. The study involves two types of treatments: a solution called octaplasLG, which contains human plasma protein, and another solution known as Plasma-Lyte® 148, which includes a mix of substances like magnesium chloride hexahydrate, potassium chloride, sodium chloride, sodium acetate trihydrate, and sodium gluconate. These solutions are given through an intravenous infusion, which means they are delivered directly into the bloodstream.

The purpose of the study is to compare the effectiveness of these two solutions in reducing blood loss during surgery for children with adolescent idiopathic scoliosis or neuromuscular scoliosis. Participants in the study will be randomly assigned to receive either the octaplasLG solution or the Plasma-Lyte® 148 solution. The study is designed to be double-blind, meaning neither the participants nor the researchers will know which solution is being administered to each participant, to ensure unbiased results.

Throughout the study, researchers will monitor various outcomes, including the amount of blood lost during surgery, the need for additional blood transfusions, and the overall recovery experience, such as pain levels and hospital stay duration. The study aims to provide valuable insights into the best fluid management practices for children undergoing spinal surgery for scoliosis.

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