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Neoplasm malignant

  • A Study of MK-1084 Alone and Combined with Cetuximab for People with Advanced Solid Tumors that Have a KRAS G12C Gene Change

    Recruiting

    2 1 1 1
    Investigated Diseases:
    • Neoplasm malignant
    Investigated Drugs:
    • Cetuximab
    • Mk-1084
    Denmark France Germany Greece Italy Norway +3

  • Study of RMC-6291 with ivonescimab drug combination in patients with advanced RAS‑mutated solid tumors

    Not yet recruiting

    1 1 1 1
    Investigated Drugs:
    • (12M)-(1S,2S)-N-((63S,4S,Z)-11-ETHYL-12-(2-((S)-1-METHOXYETHYL)-5-(4-METHYLPIPERAZIN-1-YL)PYRIDIN-3-YL)-10,10-DIMETHYL-5,7-DIOXO-61,62,63,64,65,66-HEXAHYDRO-11H-8-OXA-2(4,2)-THIAZOLA-1(5,3)-INDOLA-6(1,3)-PYRIDAZINACYCLOUNDECAPHANE-4-YL)-2-METHYLCYCLOPROPANE-1-CARBOXAMIDE
    • (2S)-2-CYCLOPENTYL-2-[(5S)-2-[(2R,3R)-3-CYCLOPROPYL-1-METHYLAZIRIDINE-2-CARBONYL]-2,7-DIAZASPIRO[4.4]NONAN-7-YL]-N-[(6S,8S,14S)-21-[5-(4-CYCLOPROPYLPIPERAZIN-1-YL)-2-[(1S)-1-METHOXYETHYL]PYRIDIN-3-YL]-18,18-DIMETHYL-9,15-DIOXO-22-(2,2,2-TRIFLUOROETHYL)-5,16-DIOXA-2,10,22,28-TETRAZAPENTACYCLO[18.5.2.12,6.110,14.023,27]NONACOSA-1(26),20,23(27),24-TETRAEN-8-YL]ACETAMIDE
    • Rmc-6291
    Belgium France Germany Greece Ireland Italy +3

  • Phase I/II study of DJI136 with drug combination in adult patients with extensive-stage small cell lung cancer

    Not yet recruiting

    2 1 1 1
    Investigated Diseases:
    • Neoplasm malignant
    • Small cell lung cancer extensive stage
    Investigated Drugs:
    • Bendamustine Hydrochloride
    • Fludarabine Phosphate
    • Cyclophosphamide
    France Spain

  • Anti‑PD1 Therapy with pembrolizumab and cemiplimab in first‑line advanced non‑small cell lung cancer patients with high PD‑L1 expression

    Not yet recruiting

    2 1 1 1
    Investigated Diseases:
    • Neoplasm malignant
    • Non-small cell lung cancer metastatic
    Investigated Drugs:
    • Cemiplimab
    • Pembrolizumab
    France

  • A study to evaluate the safety and effectiveness of H-CYS(SS)-GLU-VAL-SER-GLN-LEU-LEU-LYS-GLY-ASP-ALA-CYS(SS)-OH in patients with advanced solid tumors who have completed other treatments.

    Not yet recruiting

    2 1 1
    Investigated Diseases:
    • Neoplasm malignant
    Belgium France

  • A study to investigate the safety and effectiveness of WEF-001 in patients with advanced KRAS-mutant solid tumors

    Not yet recruiting

    1 1 1
    Investigated Drugs:
    • WEF-001
    Spain
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