Myofascial pain syndrome – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:14:28 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Myofascial pain syndrome – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Clostridium Botulinum Neurotoxin Type A for Treating Myalgia and Myofascial Pain in Patients with Temporomandibular Disorders https://clinicaltrials.eu/trial/study-on-clostridium-botulinum-neurotoxin-type-a-for-treating-myalgia-and-myofascial-pain-in-patients-with-temporomandibular-disorders/ Mon, 04 May 2026 07:56:27 +0000 https://clinicaltrials.eu/trial/study-on-clostridium-botulinum-neurotoxin-type-a-for-treating-myalgia-and-myofascial-pain-in-patients-with-temporomandibular-disorders/ This clinical trial is focused on studying the effects of a treatment for temporomandibular disorder (TMD), a condition that affects the jaw joint and muscles controlling jaw movement. The treatment being tested is an injection of Clostridium botulinum neurotoxin type A, commonly known as Botulinumtoxin A, which is a muscle relaxant. This study aims to determine if these injections can effectively reduce muscle pain in patients with TMD and whether the effectiveness depends on the dose given.

Participants in the study will receive injections of Botulinumtoxin A in specific jaw muscles, namely the masseter and temporal muscles, which are involved in chewing and jaw movement. The study will observe changes in pain levels and assess if different doses of the treatment have varying effects on pain relief. Additionally, the study will look at how the treatment impacts the quality of life, jaw function, and any psychosocial changes in participants.

The study will be conducted over a period, with participants being monitored for changes in their condition. The primary focus is on how pain levels change and whether the dose of Botulinumtoxin A matters for pain relief. Secondary observations will include improvements in quality of life and jaw function, as well as any psychosocial changes experienced by the participants. The study is expected to provide valuable insights into the treatment of myogenous TMD, which is a type of TMD caused by muscle issues.

]]> Study on Pain Relief for Fibromyalgia Patients with Trapezius Myofascial Syndrome Using Bupivacaine, Triamcinolone, and Sodium Chloride https://clinicaltrials.eu/trial/study-on-pain-relief-for-fibromyalgia-patients-with-trapezius-myofascial-syndrome-using-bupivacaine-triamcinolone-and-sodium-chloride/ Wed, 29 Apr 2026 15:03:07 +0000 https://clinicaltrials.eu/trial/study-on-pain-relief-for-fibromyalgia-patients-with-trapezius-myofascial-syndrome-using-bupivacaine-triamcinolone-and-sodium-chloride/ This clinical trial is focused on studying the treatment of pain in patients with fibromyalgia, a condition characterized by widespread pain and tenderness. Specifically, the study targets trapezius myofascial syndrome, which involves pain in the trapezius muscle, a large muscle extending over the back of the neck and shoulders. The treatment being tested involves an injection into the muscle using different substances: bupivacaine, a local anesthetic; triamcinolone acetonide, an anti-inflammatory medication; and a physiological saline solution, which is a simple saltwater solution. Some participants will receive a placebo.

The purpose of the study is to compare how effective these treatments are in reducing pain in the trapezius muscle and overall body pain in fibromyalgia patients. The study will involve injections guided by ultrasound to ensure accuracy, targeting specific areas between muscles in the shoulder region. Participants will receive these treatments and will be monitored over a period of time to assess changes in their pain levels and overall well-being.

Throughout the study, participants will be asked to report their pain levels and other symptoms at various intervals. This will help researchers understand the duration and effectiveness of the pain relief provided by each treatment. The study aims to provide insights into better managing pain for those suffering from fibromyalgia and trapezius myofascial syndrome.

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