Mydriasis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:28:29 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Mydriasis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of eye drops containing tropicamide and phenylephrine hydrochloride for pupil dilation in healthy volunteers https://clinicaltrials.eu/trial/study-on-the-effects-of-tropicamide-and-phenylephrine-hydrochloride-eye-drops-for-pupil-dilation-in-patients-needing-pre-operative-or-diagnostic-eye-exams/ Wed, 29 Apr 2026 15:05:55 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-tropicamide-and-phenylephrine-hydrochloride-eye-drops-for-pupil-dilation-in-patients-needing-pre-operative-or-diagnostic-eye-exams/ This study examines two eye medications used for pupil dilation (widening of the pupil) before surgery or for diagnostic eye examinations. The study compares a new eye drop solution containing a combination of tropicamide and phenylephrine hydrochloride against Mydriasert, which is an existing eye insert containing the same active substances.

The purpose of the study is to evaluate how effectively the new combination eye drops work in dilating the pupil compared to the currently available eye insert. The study will also assess how safe the new medication is when used in healthy volunteers. The main focus will be on measuring changes in pupil size over time after the medication is applied to the eye.

During the study, participants will receive either the new combination eye drops or the eye insert. The study will monitor how quickly and effectively the pupils dilate, and how long the effect lasts. Throughout the 6-hour observation period, researchers will take photographs of the pupils and record any discomfort or other effects experienced by the participants. The study will also track how long it takes for pupils to return to their normal size.

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