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	<title>Myasthenia gravis &#8211; European Clinical Trials Information Network</title>
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	<description>Bridging Patients with Clinical Trials</description>
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	<title>Myasthenia gravis &#8211; European Clinical Trials Information Network</title>
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	<item>
		<title>AUR200 for Patients with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/aur200-in-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Tue, 02 Jun 2026 09:56:38 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/aur200-in-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is being done in people with Generalized Myasthenia Gravis, a long-term disease that causes weakness in the muscles used for movement, breathing, and other body functions. The study is testing AUR200, also called aritinercept, which is given as a subcutaneous injection under the skin. A placebo is also used in the study. [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is being done in people with <b>Generalized Myasthenia Gravis</b>, a long-term disease that causes weakness in the muscles used for movement, breathing, and other body functions. The study is testing <b>AUR200</b>, also called aritinercept, which is given as a <b>subcutaneous injection</b> under the skin. A placebo is also used in the study. The purpose of the study is to see whether aritinercept is safe and whether it helps with this disease.</p>
<p>The study is <b>double-blind</b> and <b>randomized</b>, which means the treatment is assigned by chance and neither the participants nor the study team knows who receives which treatment during the study. The study has two parts. In the first part, the focus is on safety and how well the treatment is tolerated. In the second part, the focus is on whether the treatment helps improve symptoms over time. During the study, blood samples may be taken to look at levels of certain immune proteins, called <b>IgG</b>, <b>IgM</b>, and <b>IgA</b>, and to check for antibodies against the study drug.</p>
<p>Aritinercept is described as a <b>dual BAFF/APRIL inhibitor</b>, meaning it blocks two signals in the immune system that can help immune cells survive and stay active. This may reduce the immune attack that contributes to symptoms in generalized myasthenia gravis.</p>
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		<title>Phase 2 Randomized Study of Povetacicept to Assess Safety and Effectiveness in Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/phase-2-randomized-study-of-povetacicept-to-assess-safety-and-effectiveness-in-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Sun, 31 May 2026 04:02:45 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/phase-2-randomized-study-of-povetacicept-to-assess-safety-and-effectiveness-in-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[Generalized Myasthenia Gravis is a rare condition in which the immune system mistakenly attacks the connection between nerves and muscles, leading to muscle weakness that can affect the face, eyes, and limbs. The study evaluates the experimental drug povetacicept, which is administered by a subcutaneous injection (a shot placed just under the skin) and compared [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Generalized Myasthenia Gravis is a rare condition in which the immune system mistakenly attacks the connection between nerves and muscles, leading to muscle weakness that can affect the face, eyes, and limbs. The study evaluates the experimental drug <b>povetacicept</b>, which is administered by a <b>subcutaneous injection</b> (a shot placed just under the skin) and compared with a <b>placebo</b>, a substance that looks the same but contains no active medicine.</p>
<p>The purpose of the study is to assess whether povetacicept is safe and well‑tolerated in adults with this disease. Participants are randomly assigned to receive either the study drug or the placebo and attend regular clinic visits over several weeks, during which they receive the assigned treatment and undergo routine health checks.</p>
<p>Key assessments include measuring the level of <b>immunoglobulin G</b>, a type of antibody that helps the immune system, to see how it changes during treatment, and monitoring for any side effects or serious health problems. All observations are recorded to determine the overall safety profile of the medication.</p>
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		<title>A study testing how inebilizumab works and how safe it is in children and teenagers aged 2 to 17 years with generalized myasthenia gravis</title>
		<link>https://clinicaltrials.eu/trial/a-study-testing-how-inebilizumab-works-and-how-safe-it-is-in-children-and-teenagers-aged-2-to-17-years-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Thu, 30 Apr 2026 13:08:40 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/a-study-testing-how-inebilizumab-works-and-how-safe-it-is-in-children-and-teenagers-aged-2-to-17-years-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This study involves children and teenagers with generalized Myasthenia Gravis, a condition where the immune system attacks the connections between nerves and muscles, causing muscle weakness that can affect various parts of the body including the eyes, face, throat, and limbs. The treatment being tested is inebilizumab, also known by its code name AMG 335, [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study involves children and teenagers with <b>generalized Myasthenia Gravis</b>, a condition where the immune system attacks the connections between nerves and muscles, causing muscle weakness that can affect various parts of the body including the eyes, face, throat, and limbs. The treatment being tested is <b>inebilizumab</b>, also known by its code name <b>AMG 335</b>, which is given as an <b>infusion</b> into a vein. This medication is designed to work by targeting certain immune cells called B-cells that may play a role in causing the disease.</p>
<p>The purpose of the study is to understand how the body of children and teenagers processes <b>inebilizumab</b>, how the medication affects certain immune cells in the blood, and whether it is safe and well-tolerated in this age group. The study will measure how much of the medication is present in the blood over time, how it affects the number of specific immune cells known as <b>CD20</b>-positive B-cells, and whether any side effects occur during treatment. Participants may continue taking their current medications for myasthenia gravis, which could include steroids, other immune-suppressing medicines such as <b>azathioprine</b>, <b>mycophenolate mofetil</b>, or <b>mycophenolic acid</b>, and medications that help with muscle strength like <b>pyridostigmine</b>.</p>
<p>During the study, doctors will regularly check participants through blood tests and measurements of muscle strength and daily activities to see how the disease is responding to treatment. The study will also look at whether the body develops any immune response against the medication itself. All participants will receive the active treatment as this is an open-label study, meaning everyone will know they are receiving <b>inebilizumab</b> rather than a placebo.</p>
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		<title>A long-term safety study of KYV-101 in patients previously treated for lupus nephritis, systemic sclerosis, myasthenia gravis, rheumatoid arthritis, or stiff person syndrome</title>
		<link>https://clinicaltrials.eu/trial/a-long-term-safety-study-of-kyv-101-in-patients-previously-treated-for-lupus-nephritis-systemic-sclerosis-myasthenia-gravis-rheumatoid-arthritis-or-stiff-person-syndrome/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:09:18 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/a-long-term-safety-study-of-kyv-101-in-patients-previously-treated-for-lupus-nephritis-systemic-sclerosis-myasthenia-gravis-rheumatoid-arthritis-or-stiff-person-syndrome/</guid>

					<description><![CDATA[This study focuses on individuals who have previously received treatment with KYV-101, a medication administered through an infusion, which is a method of delivering fluids or medicine directly into a vein. The research involves people living with several different conditions, including Lupus Nephritis, which is kidney inflammation caused by an immune system problem, Systemic Sclerosis, [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on individuals who have previously received treatment with <b>KYV-101</b>, a medication administered through an <b>infusion</b>, which is a method of delivering fluids or medicine directly into a vein. The research involves people living with several different conditions, including <b>Lupus Nephritis</b>, which is kidney inflammation caused by an immune system problem, <b>Systemic Sclerosis</b>, a disease that affects connective tissues, <b>Myasthenia Gravis</b>, a condition that causes muscle weakness, <b>Rheumatoid Arthritis</b>, which affects the joints, and <b>Stiff Person Syndrome</b>, a rare disorder causing muscle stiffness. <b>Autoimmune disorders</b> are conditions where the body&#8217;s immune system mistakenly attacks its own healthy cells.</p>
<p>The purpose of the study is to evaluate the long-term safety of <b>KYV-101</b>. Participants will be monitored over an extended period to observe how the body reacts to the medication over time. This involves checking for the development of new health issues, such as <b>malignancy</b>, which refers to cancerous growths, or any changes in existing <b>neurologic</b> conditions, which are related to the brain and nervous system. The study also tracks changes in <b>rheumatologic</b> issues, which involve the joints and connective tissues, or <b>hematologic</b> disorders, which are conditions affecting the blood.</p>
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		<title>A study to evaluate the safety and effectiveness of empasiprubart and efgartigimod alfa in patients with generalized myasthenia gravis.</title>
		<link>https://clinicaltrials.eu/trial/a-study-to-evaluate-the-safety-and-effectiveness-of-empasiprubart-and-efgartigimod-alfa-in-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:09:07 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/a-study-to-evaluate-the-safety-and-effectiveness-of-empasiprubart-and-efgartigimod-alfa-in-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This study is being conducted to evaluate the safety and effectiveness of different treatment approaches for Myasthenia Gravis. This is a rare autoimmune disease where the body&#8217;s immune system mistakenly attacks the connection between nerves and muscles, leading to muscle weakness. Specifically, this research focuses on a subtype called AChR-Ab Seropositive Generalized Myasthenia Gravis, which [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study is being conducted to evaluate the safety and effectiveness of different treatment approaches for <b>Myasthenia Gravis</b>. This is a rare autoimmune disease where the body&#8217;s immune system mistakenly attacks the connection between nerves and muscles, leading to muscle weakness. Specifically, this research focuses on a subtype called <b>AChR-Ab Seropositive Generalized Myasthenia Gravis</b>, which means the disease is present throughout the body and certain antibodies, known as <b>acetylcholine receptor antibodies</b>, can be detected in the blood.</p>
<p>The research involves the use of two medications: <b>efgartigimod alfa</b> and <b>empasiprubart</b>. Both of these are administered through an <b>IV infusion</b>, which is a method of delivering medication directly into a vein. Some participants will receive <b>efgartigimod alfa</b> alone, while others will receive <b>empasiprubart</b> as an additional treatment added to their current <b>efgartigimod alfa</b> therapy. This approach is intended for individuals who have experienced only a partial improvement in their symptoms while using the first medication.</p>
<p>During the study, participants will follow a specific treatment schedule to observe how the medications affect their condition and overall health. Monitoring will include checking vital signs and conducting an <b>ECG</b>, which is a test that records the electrical activity of the heart, to ensure the treatments are tolerated well. The study aims to observe changes in how much the disease impacts daily activities and the severity of muscle weakness over time.</p>
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		<title>A study of IM-101 in adults with generalized myasthenia gravis or ocular myasthenia gravis</title>
		<link>https://clinicaltrials.eu/trial/a-study-of-im-101-in-adults-with-generalized-myasthenia-gravis-or-ocular-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:09:06 +0000</pubDate>
				<category><![CDATA[Vaccine]]></category>
		<guid isPermaLink="false">https://clinicaltrials.eu/trial/a-study-of-im-101-in-adults-with-generalized-myasthenia-gravis-or-ocular-myasthenia-gravis/</guid>

					<description><![CDATA[This study is being conducted to investigate the safety and effectiveness of the drug IM-101 in adults living with Myasthenia Gravis. This condition is a disease that causes weakness in the muscles, which can affect how a person moves, speaks, or breathes. The study focuses on two specific types: Generalized Myasthenia Gravis, where muscle weakness [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study is being conducted to investigate the safety and effectiveness of the drug <b>IM-101</b> in adults living with <b>Myasthenia Gravis</b>. This condition is a disease that causes weakness in the muscles, which can affect how a person moves, speaks, or breathes. The study focuses on two specific types: <b>Generalized Myasthenia Gravis</b>, where muscle weakness affects many parts of the body, and <b>Ocular Myasthenia Gravis</b>, which primarily affects the muscles that control the eyes. Some participants may also have specific <b>AChR antibodies</b>, which are proteins in the blood that contribute to the disease.</p>
<p>Participants in the study will receive either <b>IM-101</b> or a <b>placebo</b>, which is a substance that does not contain active medication, through an <b>intravenous injection</b>, a method where medicine is delivered directly into a vein. The research will involve different groups of people receiving various amounts of the medication to see how the body processes it and how it affects the disease. The study aims to determine if the treatment is safe, how well it is tolerated, and if it helps improve muscle strength and daily activities over a set period of time.</p>
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		<title>Study of oral cladribine compared to placebo for patients with generalized myasthenia gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-oral-cladribine-compared-to-placebo-for-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:08:31 +0000</pubDate>
				<category><![CDATA[Vaccine]]></category>
		<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-oral-cladribine-compared-to-placebo-for-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This study is looking at Generalized Myasthenia Gravis, a condition where the immune system causes muscle weakness throughout the body. The study will test a medicine called cladribine in capsule form to see if it can help people with this condition. Some participants will receive cladribine at different dose levels, while others will receive placebo. [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study is looking at <b>Generalized Myasthenia Gravis</b>, a condition where the immune system causes muscle weakness throughout the body. The study will test a medicine called <b>cladribine</b> in capsule form to see if it can help people with this condition. Some participants will receive cladribine at different dose levels, while others will receive placebo. The study will also use <b>Shingrix</b>, which is a vaccine that helps prevent shingles, a painful rash caused by the same virus that causes chickenpox.</p>
<p>The purpose of this study is to find out if cladribine capsules can improve symptoms of Generalized Myasthenia Gravis compared to placebo. The study will measure how well participants can perform daily activities and how strong their muscles are. It will also look at how cladribine affects quality of life for people living with this condition. The researchers want to understand if this treatment is safe and whether it causes any unwanted effects.</p>
<p>The study is divided into three periods and participants will be randomly assigned to receive either a high dose of cladribine, a low dose of cladribine, or placebo. During the study, participants will continue taking any other medications they were already using for their condition, such as steroids or medicines that help with muscle function. The researchers will regularly check muscle strength and the ability to do everyday tasks like talking, chewing, swallowing, and using arms and legs. Blood tests and other safety checks will be done throughout the study to monitor participants&#8217; health. If needed, some participants may receive additional treatment during the study.</p>
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		<title>A Study Comparing Nipocalimab and Efgartigimod for Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/a-study-comparing-nipocalimab-and-efgartigimod-for-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:08:21 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/a-study-comparing-nipocalimab-and-efgartigimod-for-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This study involves people with generalized myasthenia gravis, a condition where the immune system attacks the connections between nerves and muscles, causing muscle weakness and tiredness. The study will compare two medications called nipocalimab (also known as JNJ-80202135) and efgartigimod alfa. Both medications work by targeting a specific receptor in the body called the neonatal [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study involves people with <b>generalized myasthenia gravis</b>, a condition where the immune system attacks the connections between nerves and muscles, causing muscle weakness and tiredness. The study will compare two medications called <b>nipocalimab</b> (also known as <b>JNJ-80202135</b>) and <b>efgartigimod alfa</b>. Both medications work by targeting a specific receptor in the body called the <b>neonatal Fc receptor</b>, which helps reduce certain antibodies that contribute to the disease. The medications will be given through a vein. The purpose of the study is to compare how well nipocalimab works compared to efgartigimod in people who are starting treatment with this type of medication for their myasthenia gravis.</p>
<p>The study will include different groups of people. Some will receive nipocalimab, some will receive efgartigimod, and another group will include people who are already taking efgartigimod and will switch to nipocalimab during the study. People in the study must be adults between 18 and 74 years old and must have specific antibodies called <b>AChR antibodies</b> in their blood. They should also have symptoms that affect more than just their eye muscles and should not be responding well enough to their current treatment.</p>
<p>During the study, the main measurement will look at changes in the levels of a substance called <b>total IgG</b> in the blood between weeks 8 and 12 in those receiving nipocalimab compared to those receiving efgartigimod. The treatment period will last up to several months depending on which group a person is in. The study will help doctors understand whether one medication might work better than the other for treating generalized myasthenia gravis.</p>
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		<title>Study of IMVT-1402 in Adults with Mild to Severe Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-imvt-1402-in-adults-with-mild-to-severe-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:07:34 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-imvt-1402-in-adults-with-mild-to-severe-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial focuses on evaluating a new medication called IMVT-1402 for people who have Generalized Myasthenia Gravis, a condition that causes muscle weakness affecting various parts of the body. The weakness typically worsens with activity and improves with rest, making daily activities challenging for those affected. The study aims to determine how well IMVT-1402 [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial focuses on evaluating a new medication called <b>IMVT-1402</b> for people who have <b>Generalized Myasthenia Gravis</b>, a condition that causes muscle weakness affecting various parts of the body. The weakness typically worsens with activity and improves with rest, making daily activities challenging for those affected.</p>
<p>The study aims to determine how well IMVT-1402 works and how safe it is for patients with mild to severe forms of the disease. The medication is given as a <b>subcutaneous injection</b>, which means it is injected under the skin. Some participants will receive IMVT-1402, while others will receive a placebo during the study.</p>
<p>The treatment period lasts 26 weeks, during which participants will receive regular doses of either IMVT-1402 or placebo. The study will measure how the treatment affects participants&#8217; ability to perform daily activities and their overall muscle strength. Throughout the study, participants will be monitored for any changes in their condition and any potential side effects of the treatment.</p>
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		<title>Study of TOL2 safety and immune response in patients with generalized myasthenia gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-tol2-safety-and-immune-response-in-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:07:28 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-tol2-safety-and-immune-response-in-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This study focuses on patients with generalized myasthenia gravis, a condition that causes muscle weakness throughout the body. The main treatment being tested is TOL2, which is given through intravenous administration. The study will also use other medications including prednisolone, human albumin solution, glucose, and human normal immunoglobulin as part of the treatment plan. The [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on patients with <b>generalized myasthenia gravis</b>, a condition that causes muscle weakness throughout the body. The main treatment being tested is <b>TOL2</b>, which is given through <b>intravenous</b> administration. The study will also use other medications including <b>prednisolone</b>, <b>human albumin solution</b>, <b>glucose</b>, and <b>human normal immunoglobulin</b> as part of the treatment plan.</p>
<p>The purpose of this research is to evaluate if TOL2 is safe and well-tolerated by patients who have myasthenia gravis with positive <b>acetylcholine receptor antibodies</b>. This is the first time this medication is being tested in humans. The study will test both single doses and multiple doses of the medication, comparing it to placebo.</p>
<p>During the study, participants will receive either TOL2 or placebo through intravenous infusions. The study will monitor various aspects of patients&#8217; health, including their daily activities, quality of life, and any changes in their condition. Doctors will regularly check blood tests, vital signs, and perform physical examinations to ensure patient safety throughout the treatment period.</p>
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		<title>Study of Descartes-08 compared to placebo in adults with generalized myasthenia gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-descartes-08-compared-to-placebo-in-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:07:11 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-descartes-08-compared-to-placebo-in-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This study focuses on Generalized Myasthenia Gravis, a rare autoimmune disease that causes muscle weakness and fatigue affecting daily activities. The investigation examines a new treatment called Descartes-08, which consists of modified immune cells (specifically CD8+ T lymphocytes) that have been engineered to target specific proteins involved in the disease process. The research aims to [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on <b>Generalized Myasthenia Gravis</b>, a rare autoimmune disease that causes muscle weakness and fatigue affecting daily activities. The investigation examines a new treatment called <b>Descartes-08</b>, which consists of modified immune cells (specifically <b>CD8+ T lymphocytes</b>) that have been engineered to target specific proteins involved in the disease process.</p>
<p>The research aims to determine if Descartes-08 can improve the ability to perform daily activities in people with Generalized Myasthenia Gravis. The treatment is administered through <b>intravenous</b> infusion, and participants will receive either Descartes-08 or placebo. The study will monitor patients for 4 months to assess changes in their symptoms and ability to perform everyday tasks.</p>
<p>The medication being tested is a type of <b>cell therapy</b> that uses the patient&#8217;s own immune cells that have been modified in a laboratory. These cells are specifically designed to target and fight the mechanisms causing muscle weakness in Generalized Myasthenia Gravis. Throughout the study, participants will undergo regular evaluations to measure their muscle strength and daily functioning abilities.</p>
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		<title>Study on the Effects of Remibrutinib for Patients with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-effects-of-remibrutinib-for-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:04:53 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-effects-of-remibrutinib-for-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called generalized myasthenia gravis, a chronic autoimmune disease that causes muscle weakness. The study will evaluate a treatment using a medication called remibrutinib, which is taken as a film-coated tablet. Remibrutinib works by targeting and inhibiting a specific enzyme in the body known as Bruton’s tyrosine [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>generalized myasthenia gravis</i>, a chronic autoimmune disease that causes muscle weakness. The study will evaluate a treatment using a medication called <i>remibrutinib</i>, which is taken as a film-coated tablet. Remibrutinib works by targeting and inhibiting a specific enzyme in the body known as Bruton’s tyrosine kinase, which plays a role in the immune system.</p>
<p>The purpose of the study is to assess how effective, safe, and tolerable remibrutinib is for patients with generalized myasthenia gravis. Participants in the study will be randomly assigned to receive either remibrutinib or a placebo, which looks like the medication but does not contain the active ingredient. The study will be conducted in a double-blind manner, meaning neither the participants nor the researchers will know who is receiving the actual medication or the placebo. This phase of the study will last for six months, after which there will be an open-label extension phase where all participants may receive remibrutinib.</p>
<p>Throughout the study, the main focus will be on changes in the participants&#8217; ability to perform daily activities, as measured by a specific scale called the Myasthenia Gravis Activity of Daily Living (MG-ADL) scale. The study will also monitor other health indicators and any side effects that may occur. The goal is to determine if remibrutinib can help reduce the symptoms of generalized myasthenia gravis and improve the quality of life for those affected by this condition.</p>
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			</item>
		<item>
		<title>Study of Gefurulimab for Children and Teens with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-gefurulimab-for-children-and-teens-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:04:12 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-gefurulimab-for-children-and-teens-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study is specifically looking at children and teenagers aged 6 to under 18 who have a type of gMG that involves antibodies against a part of the body called the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i> (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study is specifically looking at children and teenagers aged 6 to under 18 who have a type of gMG that involves antibodies against a part of the body called the acetylcholine receptor (AChR). The treatment being tested is a medication called <i>Gefurulimab</i>, which is given as a solution for injection under the skin. This medication is also known by its code name, <i>ALXN1720</i>.</p>
<p>The purpose of the study is to understand how <i>Gefurulimab</i> works in the body, how safe it is, and how effective it is in treating children with this specific type of gMG. Participants in the study will receive the medication and be monitored over a period of time to see how their bodies respond to the treatment. The study will also look at how the medication affects the symptoms of gMG and whether it helps improve muscle strength and daily activities.</p>
<p>Throughout the study, participants will have regular check-ups to monitor their health and the effects of the medication. These check-ups will include assessments of vital signs, physical examinations, and laboratory tests. The study aims to gather important information that could help improve treatment options for children with <i>Generalized Myasthenia Gravis</i> in the future.</p>
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		<item>
		<title>Study on the Safety and Effects of YTB323 and Drug Combination for Patients with Treatment-Resistant Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-effects-of-ytb323-and-drug-combination-for-patients-with-treatment-resistant-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:02:53 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-effects-of-ytb323-and-drug-combination-for-patients-with-treatment-resistant-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called treatment-resistant generalized myasthenia gravis (gMG). This is a chronic autoimmune disease where the body&#8217;s immune system mistakenly attacks the connections between nerves and muscles, leading to muscle weakness. The study is testing a new treatment called YTB323, which is a type of cell therapy. This [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>treatment-resistant generalized myasthenia gravis</i> (gMG). This is a chronic autoimmune disease where the body&#8217;s immune system mistakenly attacks the connections between nerves and muscles, leading to muscle weakness. The study is testing a new treatment called <i>YTB323</i>, which is a type of cell therapy. This treatment involves using a patient&#8217;s own immune cells, which are modified to better fight the disease, and then infused back into the patient.</p>
<p>The purpose of the study is to assess the safety of <i>YTB323</i> in patients with gMG who have antibodies against specific proteins called AChR or MuSK. The study will also look at how the treatment affects the body over time. Participants will receive the treatment through an infusion, which is a way of delivering medication directly into the bloodstream. The study will monitor participants for any side effects and changes in their health, including vital signs and laboratory tests.</p>
<p>In addition to <i>YTB323</i>, the study involves other medications such as <i>Fludarabine Phosphate</i>, <i>Tocilizumab</i>, <i>Cyclophosphamide</i>, and <i>Flebogamma DIF</i>, which are used to prepare the body for the main treatment or manage symptoms. The study will take place over several years, with regular check-ups to track the progress and effects of the treatment. Participants will be closely monitored to ensure their safety and to gather information on how well the treatment works in managing the symptoms of gMG.</p>
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		<item>
		<title>Study on Rituximab for Patients with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-rituximab-for-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:02:32 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-rituximab-for-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Myasthenia Gravis, which is a chronic autoimmune disease that causes muscle weakness. The study aims to evaluate the effectiveness and safety of a medication called Rituximab in patients with a specific type of this disease, known as generalized AChR-antibody positive Myasthenia Gravis. Rituximab is a [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Myasthenia Gravis</i>, which is a chronic autoimmune disease that causes muscle weakness. The study aims to evaluate the effectiveness and safety of a medication called <i>Rituximab</i> in patients with a specific type of this disease, known as generalized AChR-antibody positive Myasthenia Gravis. <i>Rituximab</i> is a type of medication known as a monoclonal antibody, which is used to target and reduce certain cells in the immune system that may be contributing to the disease.</p>
<p>Participants in the study will receive <i>Rituximab</i> through an intravenous injection, which means it will be administered directly into a vein. The study will also involve the use of other medications, such as <i>Prednisone</i>, a corticosteroid taken orally in tablet form, and <i>Sodium Chloride</i>, which is a solution used for infusion. Some participants may receive a placebo instead of the active medication. The study will last for a period of up to 12 months, during which participants will have regular check-ups to monitor their health and the effects of the treatment.</p>
<p>The purpose of the study is to determine if <i>Rituximab</i> can help reduce the symptoms and improve the quality of life for people with Myasthenia Gravis. Participants will be closely monitored for any changes in their condition and any side effects they may experience. The study will also assess whether the use of <i>Rituximab</i> can lead to a reduction in the need for other medications, such as corticosteroids, which are commonly used to manage the symptoms of Myasthenia Gravis.</p>
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		<title>Study on Efgartigimod for Early Treatment in Patients with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-efgartigimod-for-early-treatment-in-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:02:18 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-efgartigimod-for-early-treatment-in-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called generalized myasthenia gravis, a disease that affects the communication between nerves and muscles, leading to muscle weakness. The study will use a treatment called efgartigimod, which is also known by its code name ARGX-113. Efgartigimod is given as a solution through an intravenous infusion, which [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>generalized myasthenia gravis</i>, a disease that affects the communication between nerves and muscles, leading to muscle weakness. The study will use a treatment called <i>efgartigimod</i>, which is also known by its code name <i>ARGX-113</i>. Efgartigimod is given as a solution through an intravenous infusion, which means it is administered directly into the bloodstream through a vein.</p>
<p>The purpose of the study is to evaluate how effective and tolerable efgartigimod is when used early in the treatment of patients with generalized myasthenia gravis. Participants in the study will receive efgartigimod along with their usual treatment regimen, which may include a medication called prednisone. The study will monitor changes in the participants&#8217; ability to perform daily activities and other health indicators over several weeks.</p>
<p>Throughout the study, participants will have regular assessments to track their progress. These assessments will occur at various intervals, such as weeks 4, 6, 8, 16, and 28, to see how the treatment affects their condition over time. The study aims to understand how quickly efgartigimod can improve symptoms and how it impacts the overall quality of life for those with generalized myasthenia gravis. Additionally, the study will observe any side effects or adverse events that may occur during the treatment period.</p>
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		<title>Study on the Safety and Tolerability of DNTH103 for Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-tolerability-of-dnth103-for-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:01:36 +0000</pubDate>
				<category><![CDATA[Vaccine]]></category>
		<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-tolerability-of-dnth103-for-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study will evaluate a treatment known as DNTH103, a monoclonal antibody, to see how safe and tolerable it is for patients with this condition. A monoclonal antibody is a type [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i> (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study will evaluate a treatment known as <i>DNTH103</i>, a monoclonal antibody, to see how safe and tolerable it is for patients with this condition. A monoclonal antibody is a type of protein made in a lab that can bind to substances in the body, including cancer cells. The trial will also include a placebo, which is a substance with no active medication, to compare the effects of DNTH103.</p>
<p>The purpose of the study is to assess the safety and tolerability of DNTH103 in adults with gMG over a period of 13 weeks. Participants will receive either DNTH103 or a placebo through intravenous (IV) or subcutaneous (SC) injections. The study will monitor the participants for any side effects and measure the levels of DNTH103 in their blood. Additionally, the study will evaluate the effectiveness of DNTH103 in improving symptoms of gMG by using various scales that measure muscle strength and daily living activities.</p>
<p>Participants in the study will be adults aged 18 to 75 who have been diagnosed with gMG for at least three months. They will need to have received certain vaccinations against bacterial infections before joining the study. The trial will last up to 52 weeks, with the main focus on the first 13 weeks. During this time, the safety and any potential side effects of DNTH103 will be closely monitored. The study aims to provide valuable information on the potential benefits and risks of using DNTH103 for treating gMG.</p>
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		<item>
		<title>Study on Long-Term Safety and Effectiveness of Zilucoplan in Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-long-term-safety-and-effectiveness-of-zilucoplan-in-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:01:26 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-long-term-safety-and-effectiveness-of-zilucoplan-in-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the long-term safety and effectiveness of a treatment called zilucoplan sodium for individuals with generalized myasthenia gravis. Generalized myasthenia gravis is a chronic autoimmune disease that causes muscle weakness. The treatment being tested, zilucoplan sodium, is administered as a solution for injection using a pre-filled syringe. It is [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the long-term safety and effectiveness of a treatment called <i>zilucoplan sodium</i> for individuals with <i>generalized myasthenia gravis</i>. Generalized myasthenia gravis is a chronic autoimmune disease that causes muscle weakness. The treatment being tested, zilucoplan sodium, is administered as a solution for injection using a pre-filled syringe. It is designed to be self-administered by patients through a subcutaneous injection, which means it is injected under the skin.</p>
<p>The purpose of this study is to evaluate how safe and tolerable zilucoplan sodium is for patients who have already participated in a previous study involving this medication. Participants will receive the treatment over an extended period to monitor its effects and any potential side effects. The study will not involve any new medications or diseases, focusing solely on zilucoplan sodium and generalized myasthenia gravis.</p>
<p>Throughout the study, participants will be regularly assessed to ensure their well-being and to gather information on how the treatment impacts their daily activities and quality of life. The study aims to provide valuable insights into the long-term use of zilucoplan sodium for managing symptoms of generalized myasthenia gravis.</p>
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		<item>
		<title>Study of Efgartigimod PH20 SC for Children Aged 2 to 17 with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-efgartigimod-ph20-sc-for-children-aged-2-to-17-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:01:25 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-efgartigimod-ph20-sc-for-children-aged-2-to-17-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis, which is a chronic autoimmune disease that causes muscle weakness. The study involves a treatment called efgartigimod PH20 SC, which is a solution for injection. This treatment is being tested in children aged 2 to less than 18 years who have this [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i>, which is a chronic autoimmune disease that causes muscle weakness. The study involves a treatment called <i>efgartigimod PH20 SC</i>, which is a solution for injection. This treatment is being tested in children aged 2 to less than 18 years who have this condition. The purpose of the study is to confirm the appropriate dose of this treatment for young patients with Generalized Myasthenia Gravis.</p>
<p>Participants in the study will receive the treatment through a subcutaneous injection, which means it is injected under the skin. The study will monitor how the body processes the treatment and its effects on the disease. This includes checking the levels of certain proteins in the blood and observing any changes in the symptoms of Generalized Myasthenia Gravis. The study will also look at the safety of the treatment by recording any side effects and changes in health indicators like heart rate and blood tests.</p>
<p>The study will take place over a period of time, during which participants will have regular check-ups to assess their response to the treatment. The goal is to gather information that will help determine the best way to use efgartigimod PH20 SC in treating children with Generalized Myasthenia Gravis. This research is important for understanding how to manage this condition in younger patients and improve their quality of life.</p>
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		<item>
		<title>Study on the Effects of Efgartigimod Alfa for Patients with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-effects-of-efgartigimod-alfa-for-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:59:46 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-effects-of-efgartigimod-alfa-for-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study is testing a treatment called efgartigimod alfa, which is given through an intravenous infusion, meaning it is administered directly into the bloodstream through a vein. The purpose of the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i> (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study is testing a treatment called <i>efgartigimod alfa</i>, which is given through an intravenous infusion, meaning it is administered directly into the bloodstream through a vein. The purpose of the study is to evaluate how different dosing schedules of efgartigimod alfa can maximize and maintain clinical benefits for patients with gMG.</p>
<p>Participants in the study will receive efgartigimod alfa in one of two dosing regimens. The study will compare a continuous regimen, where the medication is given every two weeks, to a cyclic regimen, where the medication is given in cycles. The study will monitor changes in the participants&#8217; symptoms over time to determine which dosing schedule is more effective. The study will also track any side effects or adverse events that participants may experience during the trial.</p>
<p>The trial aims to provide valuable information on how to best use efgartigimod alfa to help manage symptoms of Generalized Myasthenia Gravis. By comparing different dosing regimens, researchers hope to find the most effective way to use this treatment to improve the quality of life for individuals living with this condition.</p>
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		<title>Study on Efgartigimod IV for Adults with Seronegative Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-efgartigimod-iv-for-adults-with-seronegative-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:58:49 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-efgartigimod-iv-for-adults-with-seronegative-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition known as Generalized Myasthenia Gravis, specifically in patients who do not have certain antibodies called acetylcholine receptor binding antibodies. This condition is a chronic autoimmune disorder that causes muscle weakness. The study will evaluate a treatment called Efgartigimod IV, which is a medication given through an [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition known as <i>Generalized Myasthenia Gravis</i>, specifically in patients who do not have certain antibodies called acetylcholine receptor binding antibodies. This condition is a chronic autoimmune disorder that causes muscle weakness. The study will evaluate a treatment called <i>Efgartigimod IV</i>, which is a medication given through an intravenous infusion. This means the medicine is delivered directly into the bloodstream through a vein. The purpose of the study is to determine how effective and safe this treatment is compared to a placebo in managing the symptoms of this condition.</p>
<p>Participants in the study will receive either the <i>Efgartigimod IV</i> treatment or a placebo. The study is designed to be double-blinded, meaning neither the participants nor the researchers will know who is receiving the actual treatment or the placebo. This helps ensure that the results are unbiased. The study will follow a structured plan over a period of time, during which participants will be monitored for changes in their symptoms and any side effects they may experience.</p>
<p>The trial aims to provide valuable information about the potential benefits of <i>Efgartigimod IV</i> for people with <i>Generalized Myasthenia Gravis</i> who are seronegative for acetylcholine receptor binding antibodies. By comparing the effects of the treatment to those of a placebo, researchers hope to better understand how this medication can help manage the condition and improve the quality of life for those affected. Participants will be closely observed throughout the study to ensure their safety and to gather comprehensive data on the treatment&#8217;s impact.</p>
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		<item>
		<title>Study on the Long-term Safety of Efgartigimod for Children with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-long-term-safety-of-efgartigimod-for-children-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:57:22 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-long-term-safety-of-efgartigimod-for-children-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the long-term safety of a treatment for Generalized Myasthenia Gravis, a chronic autoimmune disease that causes muscle weakness. The treatment being tested is called efgartigimod, which is administered in two forms: intravenously (through a vein) and subcutaneously (under the skin). The study aims to evaluate how safe and [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the long-term safety of a treatment for <i>Generalized Myasthenia Gravis</i>, a chronic autoimmune disease that causes muscle weakness. The treatment being tested is called <i>efgartigimod</i>, which is administered in two forms: intravenously (through a vein) and subcutaneously (under the skin). The study aims to evaluate how safe and well-tolerated these forms of efgartigimod are when given to children with this condition.</p>
<p>Participants in the study will receive either the intravenous or subcutaneous form of efgartigimod over a period of time. The study will monitor the occurrence and severity of any side effects, as well as changes in laboratory test results, vital signs, and other health indicators. The study will also look at the presence of any antibodies that might develop against efgartigimod or the enzyme used in the subcutaneous form, known as recombinant human hyaluronidase PH20.</p>
<p>The purpose of this study is to ensure that the treatment is safe for long-term use in children with <i>Generalized Myasthenia Gravis</i>. By carefully observing the effects of the treatment, researchers hope to gather important information that could lead to better management of this condition in the future.</p>
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		<title>Study on the Safety and Effectiveness of Rozanolixizumab in Children with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-rozanolixizumab-in-children-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:57:20 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-rozanolixizumab-in-children-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis, which is a chronic autoimmune disease that causes muscle weakness. The study is investigating a treatment called Rozanolixizumab, also known by its code name UCB7665. Rozanolixizumab is given as a solution for injection under the skin, a method known as subcutaneous use. [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i>, which is a chronic autoimmune disease that causes muscle weakness. The study is investigating a treatment called <i>Rozanolixizumab</i>, also known by its code name <i>UCB7665</i>. Rozanolixizumab is given as a solution for injection under the skin, a method known as subcutaneous use. The purpose of the study is to assess the safety and how well this treatment is tolerated in children aged 2 to under 18 years who have moderate to severe generalized myasthenia gravis.</p>
<p>Participants in the study will receive Rozanolixizumab over a period of six weeks. During this time, researchers will monitor how the drug moves through the body and its effects on the disease. The study will also look at any side effects that may occur, including serious ones that might lead to stopping the treatment. Additionally, the study will measure changes in certain proteins in the blood, known as immunoglobulins, and specific antibodies related to myasthenia gravis. These measurements will help determine if the treatment is working and how it affects the participants&#8217; daily activities and overall condition.</p>
<p>The study is designed to last up to 18 weeks, including the treatment and observation periods. Throughout the study, researchers will evaluate the local tolerability of the treatment, which means they will check how the skin and body react to the injections. The study aims to provide valuable information on the potential benefits and risks of using Rozanolixizumab in young patients with generalized myasthenia gravis, contributing to better understanding and management of this condition.</p>
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		<title>Study on the Safety and Effectiveness of Rozanolixizumab and Immunoglobulins in Children with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-rozanolixizumab-and-immunoglobulins-in-children-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:57:07 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-rozanolixizumab-and-immunoglobulins-in-children-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called generalized myasthenia gravis, which is a chronic autoimmune disorder that causes muscle weakness. The study is investigating a treatment called rozanolixizumab, also known by its code name UCB7665. Rozanolixizumab is a solution for injection that is being tested to see if it is safe and [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>generalized myasthenia gravis</i>, which is a chronic autoimmune disorder that causes muscle weakness. The study is investigating a treatment called <i>rozanolixizumab</i>, also known by its code name UCB7665. Rozanolixizumab is a solution for injection that is being tested to see if it is safe and effective for children with this condition. The purpose of the study is to assess the long-term safety and tolerability of multiple treatment cycles with rozanolixizumab in pediatric participants.</p>
<p>Participants in the study will receive treatment cycles with rozanolixizumab over a period of time. The study will monitor for any serious side effects or adverse events that may occur during the treatment. Additionally, the study will look at changes in the levels of a protein in the blood called <i>Immunoglobulin G (IgG)</i>, which plays a role in the immune system, as well as changes in the symptoms of myasthenia gravis. The study aims to provide valuable information on how well the treatment works and how safe it is for children with generalized myasthenia gravis.</p>
<p>Throughout the study, participants will be closely observed to ensure their safety and to gather data on the effectiveness of rozanolixizumab. The study is designed to help understand if this treatment can be a viable option for managing symptoms in children with generalized myasthenia gravis, potentially improving their quality of life. The study is expected to continue until 2027, providing a comprehensive evaluation of the treatment&#8217;s impact over time.</p>
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		<title>Study on Corticosteroids and Rituximab to Prevent Worsening of Ocular Myasthenia Gravis in Newly Diagnosed Patients</title>
		<link>https://clinicaltrials.eu/trial/study-on-corticosteroids-and-rituximab-to-prevent-worsening-of-ocular-myasthenia-gravis-in-newly-diagnosed-patients/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:47:34 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-corticosteroids-and-rituximab-to-prevent-worsening-of-ocular-myasthenia-gravis-in-newly-diagnosed-patients/</guid>

					<description><![CDATA[This clinical trial focuses on studying a condition called ocular myasthenia gravis, which affects the muscles around the eyes, causing symptoms like drooping eyelids and double vision. The study aims to explore the effectiveness of a treatment plan that includes immediate use of corticosteroids, a type of medication that helps reduce inflammation, and the addition [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial focuses on studying a condition called <i>ocular myasthenia gravis</i>, which affects the muscles around the eyes, causing symptoms like drooping eyelids and double vision. The study aims to explore the effectiveness of a treatment plan that includes immediate use of <i>corticosteroids</i>, a type of medication that helps reduce inflammation, and the addition of <i>rituximab</i>, a medication that targets specific cells in the immune system, if symptoms return while reducing the corticosteroid dosage. The goal is to prevent the condition from spreading to other muscles in the body over a period of two years.</p>
<p>Participants in the study will receive either the treatment plan involving corticosteroids and rituximab or a different approach, which may include a <i>placebo</i>. The study will monitor the participants over time to see how many develop generalized myasthenia gravis, where symptoms affect more than just the eye muscles. The study will also compare the severity of symptoms, the number of hospital visits, and the quality of life between the two groups.</p>
<p>The medications used in this study include <i>POLARAMINE</i> (dexchlorpheniramine maleate), <i>IMUREL</i> (azathioprine), <i>Rixathon</i> (rituximab), <i>PARACETAMOL PANPHARMA</i> (paracetamol), <i>CORTANCYL</i> (prednisone), and <i>SOLUMEDROL</i> (methylprednisolone hemisuccinate). These medications are administered in various forms, such as injections or tablets, depending on the specific treatment plan. The study will last for several years, with regular check-ups to assess the effectiveness and safety of the treatments.</p>
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		<item>
		<title>Study on Ublituximab and Drug Combination for Patients with Myasthenia Gravis or Relapsing Multiple Sclerosis</title>
		<link>https://clinicaltrials.eu/trial/study-on-ublituximab-and-drug-combination-for-patients-with-myasthenia-gravis-or-relapsing-multiple-sclerosis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:29:40 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-ublituximab-and-drug-combination-for-patients-with-myasthenia-gravis-or-relapsing-multiple-sclerosis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the effects of a medication called ublituximab in patients with certain autoimmune diseases, specifically Myasthenia Gravis and Relapsing Multiple Sclerosis. Autoimmune diseases occur when the body&#8217;s immune system mistakenly attacks its own tissues. Ublituximab is a type of medication known as a monoclonal antibody, which is designed to [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the effects of a medication called <u>ublituximab</u> in patients with certain autoimmune diseases, specifically <u>Myasthenia Gravis</u> and <u>Relapsing Multiple Sclerosis</u>. Autoimmune diseases occur when the body&#8217;s immune system mistakenly attacks its own tissues. <u>Ublituximab</u> is a type of medication known as a monoclonal antibody, which is designed to target specific cells in the immune system. The purpose of this study is to understand how the body processes and responds to <u>ublituximab</u> when it is given either through a vein (intravenous) or under the skin (subcutaneous).</p>
<p>During the study, participants will receive <u>ublituximab</u> and may also receive other medications such as <u>methylprednisolone</u>, <u>cetirizine</u>, <u>paracetamol</u>, <u>diphenhydramine</u>, <u>dexamethasone</u>, and <u>sodium chloride</u>. These medications are commonly used to manage symptoms or support the treatment process. The study will monitor how <u>ublituximab</u> is absorbed, distributed, and eliminated by the body, as well as its effects on certain immune cells called B-cells.</p>
<p>The trial will take place over several years, with participants attending regular visits to receive the medication and undergo assessments. These assessments will help researchers gather important information about the safety and effectiveness of <u>ublituximab</u> in treating these autoimmune conditions. The study aims to provide valuable insights that could improve treatment options for patients with <u>Myasthenia Gravis</u> and <u>Relapsing Multiple Sclerosis</u>.</p>
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		<item>
		<title>Study on the Effects of Inebilizumab for Adults with Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-effects-of-inebilizumab-for-adults-with-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:29:36 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-effects-of-inebilizumab-for-adults-with-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the effects of a treatment called inebilizumab on a condition known as myasthenia gravis. Myasthenia gravis is a disease that causes weakness in the muscles, and it can be due to specific antibodies, which are proteins in the body that mistakenly attack healthy cells. These antibodies are called [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the effects of a treatment called <i>inebilizumab</i> on a condition known as <i>myasthenia gravis</i>. Myasthenia gravis is a disease that causes weakness in the muscles, and it can be due to specific antibodies, which are proteins in the body that mistakenly attack healthy cells. These antibodies are called <i>acetylcholine receptor antibodies (AChR)</i> or <i>muscle-specific kinase antibodies (MuSK)</i>. The treatment being tested, inebilizumab, is given as an injection into a vein, and it is being studied to see if it can help reduce the disability caused by myasthenia gravis.</p>
<p>The study is designed to compare the effects of inebilizumab with a placebo, which is a substance with no active medication. Participants in the study will receive either inebilizumab or the placebo. The study will last for a period of time, during which participants will receive regular doses of the treatment. The goal is to observe any changes in the participants&#8217; ability to perform daily activities and to assess the overall safety and effectiveness of inebilizumab.</p>
<p>Throughout the study, participants will be monitored for any side effects or changes in their condition. The study will also look at how inebilizumab affects the use of other medications, such as corticosteroids, which are often used to manage myasthenia gravis. By the end of the study, researchers hope to determine if inebilizumab can provide a meaningful improvement in the lives of those living with myasthenia gravis.</p>
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		<title>Study on the Safety and Effectiveness of Gefurulimab for Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-gefurulimab-for-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:29:29 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-gefurulimab-for-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the disease known as Generalized Myasthenia Gravis, a condition that causes muscle weakness due to the immune system attacking the communication between nerves and muscles. The study will evaluate a treatment called Gefurulimab, which is administered as a solution for injection. This treatment is being compared to a [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the disease known as <i>Generalized Myasthenia Gravis</i>, a condition that causes muscle weakness due to the immune system attacking the communication between nerves and muscles. The study will evaluate a treatment called <i>Gefurulimab</i>, which is administered as a solution for injection. This treatment is being compared to a placebo to assess its effectiveness and safety in managing the symptoms of this disease.</p>
<p>The purpose of the study is to determine how well <i>Gefurulimab</i> works in improving the daily living activities of adults with <i>Generalized Myasthenia Gravis</i>. Participants in the study will receive either the treatment or a placebo and will be monitored over a period of time to observe any changes in their condition. The study aims to see if there is a significant improvement in the ability to perform daily activities and a reduction in muscle weakness.</p>
<p>Throughout the study, participants will undergo regular assessments to track their progress and any changes in their symptoms. The study is designed to provide valuable information on the potential benefits of <i>Gefurulimab</i> for individuals living with <i>Generalized Myasthenia Gravis</i>, contributing to the understanding of how this treatment can help manage the disease.</p>
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		<title>Study of KYV-101 Therapy for Patients with Refractory Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-of-kyv-101-therapy-for-patients-with-refractory-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:29:28 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-kyv-101-therapy-for-patients-with-refractory-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called refractory generalized myasthenia gravis. This is a chronic autoimmune disease where the body&#8217;s immune system mistakenly attacks the communication between nerves and muscles, leading to muscle weakness. The study is testing a new treatment called KYV-101, which is a type of cell therapy. Specifically, it [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>refractory generalized myasthenia gravis</i>. This is a chronic autoimmune disease where the body&#8217;s immune system mistakenly attacks the communication between nerves and muscles, leading to muscle weakness. The study is testing a new treatment called <i>KYV-101</i>, which is a type of cell therapy. Specifically, it uses a technique called <i>Chimeric Antigen Receptor T-Cell (CAR T) therapy</i>. This involves using the patient&#8217;s own immune cells, which are modified to better recognize and attack certain targets in the body.</p>
<p>The purpose of the study is to understand how safe and tolerable <i>KYV-101</i> is for patients, as well as how effective it might be in treating the disease. Participants in the study will receive the treatment through an <i>intravenous infusion</i>, which means the medicine is given directly into a vein. The study will follow participants over a period of time to monitor their health and any changes in their condition. This includes checking for any side effects and measuring the strength and function of their muscles.</p>
<p>Throughout the study, researchers will collect information on various health markers, such as the presence of specific antibodies and the levels of certain cells in the blood. This will help them understand how the treatment is working and its impact on the disease. The study aims to provide valuable insights into the potential benefits of <i>KYV-101</i> for people living with refractory generalized myasthenia gravis.</p>
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		<title>Study on the Safety and Effectiveness of NMD670 for Adults with Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-nmd670-for-adults-with-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:28:21 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-nmd670-for-adults-with-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the effects of a new treatment called NMD670 for patients with Myasthenia Gravis. Myasthenia Gravis is a condition that causes weakness in the muscles that control movements, often affecting the eyes, face, and swallowing. The study will test three different dose levels of NMD670, which is taken as [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the effects of a new treatment called <b>NMD670</b> for patients with <b>Myasthenia Gravis</b>. Myasthenia Gravis is a condition that causes weakness in the muscles that control movements, often affecting the eyes, face, and swallowing. The study will test three different dose levels of NMD670, which is taken as a tablet, to see how well it works and how safe it is for patients.</p>
<p>The purpose of the study is to evaluate the effectiveness and safety of NMD670 over a period of 21 days. Participants will be randomly assigned to receive either NMD670 or a placebo, which looks like the real medication but does not contain the active substance. The study is designed to be double-blind, meaning neither the participants nor the researchers will know who is receiving the actual medication or the placebo during the trial.</p>
<p>Throughout the study, participants will take the medication orally and will be monitored by healthcare professionals to assess any changes in their condition. The main goal is to observe any improvements in muscle strength and overall symptoms of Myasthenia Gravis. The study aims to provide valuable information on the potential benefits of NMD670 for managing this condition.</p>
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		<title>Study on Efgartigimod for Children Aged 2-17 with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-efgartigimod-for-children-aged-2-17-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:28:03 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-efgartigimod-for-children-aged-2-17-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis, a chronic autoimmune disease that causes muscle weakness. The trial is testing a treatment called efgartigimod alfa, which is given as an intravenous infusion. The purpose of the study is to find the best dose of efgartigimod alfa for children aged 2 [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i>, a chronic autoimmune disease that causes muscle weakness. The trial is testing a treatment called <i>efgartigimod alfa</i>, which is given as an intravenous infusion. The purpose of the study is to find the best dose of efgartigimod alfa for children aged 2 to less than 18 years who have this condition.</p>
<p>Participants in the study will receive efgartigimod alfa through a vein, and the study will monitor how the body processes the medication and how it affects the disease. The study will also look at the safety of the treatment and any side effects that may occur. The trial aims to provide evidence of how well the treatment works in children with Generalized Myasthenia Gravis.</p>
<p>Throughout the study, researchers will collect information on the levels of certain proteins in the blood, such as total <i>IgG</i> and anti-acetylcholine receptor antibodies, which are important in understanding the disease and the treatment&#8217;s effects. The study will also assess changes in the participants&#8217; quality of life and any improvements in their symptoms. The trial is expected to continue until March 2025.</p>
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		<title>Study on the Effects of Iptacopan in Patients with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-effects-of-iptacopan-in-patients-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:27:59 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-effects-of-iptacopan-in-patients-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a disease called generalized Myasthenia Gravis (gMG), which is a condition that causes muscle weakness. The study will evaluate a treatment called iptacopan, which is taken as a capsule. The purpose of the study is to assess how effective and safe iptacopan is for people with gMG. Participants [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a disease called <i>generalized Myasthenia Gravis</i> (gMG), which is a condition that causes muscle weakness. The study will evaluate a treatment called <i>iptacopan</i>, which is taken as a capsule. The purpose of the study is to assess how effective and safe iptacopan is for people with gMG. Participants in the study will either receive iptacopan or a placebo, which looks like the treatment but does not contain the active medicine.</p>
<p>The study will begin with a phase where neither the participants nor the researchers know who is receiving iptacopan and who is receiving the placebo. This is known as a &#8220;double-blind&#8221; study. After this phase, there will be an &#8220;open label&#8221; phase where all participants will receive iptacopan. The study will last for several months, and participants will be monitored to see how their symptoms change over time. The main goal is to see if iptacopan can help reduce the symptoms of gMG, as measured by a specific scale that assesses daily living activities affected by the disease.</p>
<p>Throughout the study, participants will have regular check-ups to monitor their health and any changes in their condition. The study will also look at any side effects that might occur with the use of iptacopan. This research aims to provide more information about the potential benefits and risks of using iptacopan for treating generalized Myasthenia Gravis.</p>
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		<title>Study on Vimseltinib for Patients with Tenosynovial Giant Cell Tumor</title>
		<link>https://clinicaltrials.eu/trial/study-on-vimseltinib-for-patients-with-tenosynovial-giant-cell-tumor/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:27:52 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-vimseltinib-for-patients-with-tenosynovial-giant-cell-tumor/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition known as Tenosynovial Giant Cell Tumor (TGCT). TGCT is a type of tumor that affects the joints and can cause pain and stiffness. The study is testing a new treatment called Vimseltinib, which is taken as a capsule. The purpose of the study is to evaluate [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition known as <i>Tenosynovial Giant Cell Tumor</i> (TGCT). TGCT is a type of tumor that affects the joints and can cause pain and stiffness. The study is testing a new treatment called <i>Vimseltinib</i>, which is taken as a capsule. The purpose of the study is to evaluate how effective and safe Vimseltinib is for patients with TGCT.</p>
<p>The study is divided into two parts. In the first part, participants will be randomly assigned to receive either Vimseltinib or a <i>placebo</i>, which looks like the medication but does not contain the active ingredient. This part of the study is double-blind, meaning neither the participants nor the researchers will know who is receiving the actual medication. In the second part, all participants will receive Vimseltinib, and this phase is open-label, meaning everyone will know they are receiving the medication.</p>
<p>Participants will take the medication orally and will be monitored over a period of time to assess the response of their tumor to the treatment. The study will also look at changes in joint movement, pain levels, and overall physical function. The goal is to see if Vimseltinib can reduce the size of the tumor and improve symptoms without causing significant side effects. The study will help determine if Vimseltinib is a viable treatment option for people with Tenosynovial Giant Cell Tumor.</p>
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		<title>Study on the Effectiveness and Safety of Batoclimab for Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-batoclimab-for-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:27:36 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-effectiveness-and-safety-of-batoclimab-for-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis (gMG), which is a chronic autoimmune disease that causes muscle weakness. The study is testing a treatment called Batoclimab, also known by its code name IMVT-1401. Batoclimab is a solution for injection that is administered under the skin. The trial will compare [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis (gMG)</i>, which is a chronic autoimmune disease that causes muscle weakness. The study is testing a treatment called <i>Batoclimab</i>, also known by its code name <i>IMVT-1401</i>. Batoclimab is a solution for injection that is administered under the skin. The trial will compare the effects of Batoclimab to a placebo, which looks like the treatment but does not contain any active ingredients.</p>
<p>The purpose of the study is to evaluate how effective and safe Batoclimab is as a treatment for adults with Generalized Myasthenia Gravis. Participants in the study will receive either Batoclimab or a placebo. The study will monitor changes in the participants&#8217; ability to perform daily activities, which is an important measure of how the disease affects their lives. The trial will last for several weeks, during which participants will receive regular injections and attend follow-up visits to assess their progress.</p>
<p>Throughout the study, researchers will carefully observe the participants to see how their symptoms change and to ensure their safety. The goal is to determine if Batoclimab can help improve the quality of life for people living with Generalized Myasthenia Gravis by reducing muscle weakness and improving their ability to carry out daily tasks. This study is an important step in finding new and effective treatments for this challenging condition.</p>
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		<title>Study on the Safety and Effectiveness of Zilucoplan Auto-Injector for Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-zilucoplan-auto-injector-for-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:27:18 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-zilucoplan-auto-injector-for-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying Generalized Myasthenia Gravis, a condition that causes muscle weakness. The study will use a treatment called Zilucoplan sodium, which is a medication designed to help manage this condition. The medication is administered through a pre-filled pen that allows for easy self-injection under the skin. The purpose of the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying <i>Generalized Myasthenia Gravis</i>, a condition that causes muscle weakness. The study will use a treatment called <i>Zilucoplan sodium</i>, which is a medication designed to help manage this condition. The medication is administered through a pre-filled pen that allows for easy self-injection under the skin.</p>
<p>The purpose of the study is to evaluate the safety and effectiveness of using the <i>Zilucoplan</i> auto-injector for self-administration by participants with <i>Generalized Myasthenia Gravis</i>. Participants will be asked to use the auto-injector to administer the medication themselves. The study will monitor how well participants can manage the self-injection process and will also keep track of any side effects or adverse reactions that may occur during the study period.</p>
<p>The study will take place over several visits, where participants will be observed and supported in using the auto-injector. The goal is to ensure that the auto-injector is a safe and effective way for people with <i>Generalized Myasthenia Gravis</i> to manage their treatment independently. Participants will be closely monitored for any serious or non-serious side effects related to the medication or the device used for administration.</p>
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		<title>Study on Nipocalimab for Adults with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-nipocalimab-for-adults-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:26:59 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-nipocalimab-for-adults-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called Generalized Myasthenia Gravis, a disease that causes muscle weakness. The study is testing a treatment called nipocalimab, which is given as an infusion, meaning it is delivered directly into the bloodstream through a vein. The trial will compare the effects of nipocalimab to a placebo, [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>Generalized Myasthenia Gravis</i>, a disease that causes muscle weakness. The study is testing a treatment called <i>nipocalimab</i>, which is given as an infusion, meaning it is delivered directly into the bloodstream through a vein. The trial will compare the effects of nipocalimab to a placebo, which is a substance with no active medication, to see how well it works and how safe it is for people with this condition.</p>
<p>The main goal of the study is to evaluate how effective nipocalimab is in improving the daily living activities of people with Generalized Myasthenia Gravis. Participants in the study will receive either nipocalimab or a placebo, and their progress will be monitored over a period of time. The study will look at changes in their ability to perform daily activities and any side effects they might experience.</p>
<p>Participants will be randomly assigned to receive either the treatment or the placebo, and neither the participants nor the researchers will know who is receiving which, to ensure unbiased results. The study will take place over several weeks, and participants will have regular check-ups to assess their health and the effects of the treatment. The information gathered from this study will help determine if nipocalimab is a safe and effective treatment option for people with Generalized Myasthenia Gravis.</p>
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		<title>Study on Zilucoplan Sodium for Children Aged 2 to 17 with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-zilucoplan-sodium-for-children-aged-2-to-17-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:25:54 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-zilucoplan-sodium-for-children-aged-2-to-17-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called generalized myasthenia gravis, which is a chronic autoimmune disease that causes muscle weakness. The study is specifically looking at children aged 2 to less than 18 years who have this condition. The treatment being tested is a medication called zilucoplan sodium, which is given as [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>generalized myasthenia gravis</i>, which is a chronic autoimmune disease that causes muscle weakness. The study is specifically looking at children aged 2 to less than 18 years who have this condition. The treatment being tested is a medication called <i>zilucoplan sodium</i>, which is given as an injection under the skin. The purpose of the study is to understand how zilucoplan moves through the body over time and to assess its safety in children with generalized myasthenia gravis.</p>
<p>Participants in the study will receive zilucoplan sodium once a day for a period of time. The study will monitor how the medication affects the body and any side effects that may occur. The study will also look at changes in the participants&#8217; ability to perform daily activities and their overall quality of life. Some participants may receive a placebo, which is a substance with no active medication, to compare the effects of zilucoplan sodium.</p>
<p>The study aims to gather information on how zilucoplan sodium can help manage symptoms of generalized myasthenia gravis in children and to ensure it is safe for use in this age group. The results will help determine if this treatment can be a beneficial option for managing this condition in young patients.</p>
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		<title>Study on the Long-Term Safety of Zilucoplan in Children with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-long-term-safety-of-zilucoplan-in-children-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:25:42 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-long-term-safety-of-zilucoplan-in-children-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying the long-term safety and effects of a medication called zilucoplan sodium in children with a condition known as generalized myasthenia gravis. Generalized myasthenia gravis is a chronic autoimmune disease that causes muscle weakness. The medication, zilucoplan sodium, is administered as a solution for injection under the skin using [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the long-term safety and effects of a medication called <i>zilucoplan sodium</i> in children with a condition known as <i>generalized myasthenia gravis</i>. Generalized myasthenia gravis is a chronic autoimmune disease that causes muscle weakness. The medication, zilucoplan sodium, is administered as a solution for injection under the skin using a pre-filled syringe. The study aims to understand how safe and tolerable zilucoplan sodium is when used over an extended period.</p>
<p>Participants in this study will receive zilucoplan sodium through daily injections for up to 52 weeks. The study will monitor the occurrence of any side effects or adverse events that may arise during this period. Additionally, the study will assess the levels of zilucoplan sodium in the blood and its impact on certain biological markers related to the disease. The study will also evaluate how the medication affects the participants&#8217; ability to perform daily activities and their overall muscle strength.</p>
<p>This study is an extension of a previous research project involving zilucoplan sodium, and it is designed to provide further insights into the medication&#8217;s long-term use in treating generalized myasthenia gravis in children. Participants who have completed the earlier study and for whom continued treatment is deemed beneficial by their healthcare provider may be eligible to participate in this extension study.</p>
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		<title>Study on Nipocalimab for Children Aged 2-17 with Generalized Myasthenia Gravis</title>
		<link>https://clinicaltrials.eu/trial/study-on-nipocalimab-for-children-aged-2-17-with-generalized-myasthenia-gravis/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:23:55 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-nipocalimab-for-children-aged-2-17-with-generalized-myasthenia-gravis/</guid>

					<description><![CDATA[This clinical trial is focused on studying a condition called generalized myasthenia gravis, which is a disease that causes muscle weakness. The study is specifically for children and teenagers aged 2 to less than 18 years who have this condition. The treatment being tested is a medication called nipocalimab, which is given as a solution [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition called <i>generalized myasthenia gravis</i>, which is a disease that causes muscle weakness. The study is specifically for children and teenagers aged 2 to less than 18 years who have this condition. The treatment being tested is a medication called <i>nipocalimab</i>, which is given as a solution through an infusion into a vein. The purpose of the study is to evaluate how well nipocalimab works, how safe it is, and how it behaves in the body of young patients with generalized myasthenia gravis who have not responded well to their current treatment.</p>
<p>Participants in the study will receive nipocalimab and will be monitored over a period of time to see how their bodies respond to the treatment. The study will look at various aspects, such as the effect of nipocalimab on certain proteins in the blood and any side effects that may occur. The study aims to gather information on how the medication is processed in the body and its overall impact on the disease.</p>
<p>This trial is open-label, meaning that both the participants and the researchers know what treatment is being given. The study does not involve a placebo, and all participants will receive the active medication. The information collected from this study will help in understanding the potential benefits and risks of using nipocalimab in treating generalized myasthenia gravis in children and teenagers.</p>
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		<title>Study on Cladribine for Treating Seropositive Myasthenia Gravis in Patients</title>
		<link>https://clinicaltrials.eu/trial/study-on-cladribine-for-treating-seropositive-myasthenia-gravis-in-patients/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:23:09 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-cladribine-for-treating-seropositive-myasthenia-gravis-in-patients/</guid>

					<description><![CDATA[This clinical trial is focused on studying the disease known as Myasthenia Gravis, a condition that causes weakness in the muscles that control voluntary movements. The trial is investigating the use of a medication called Cladribine, which is being added to the current treatment plan for patients with a specific type of this disease, known [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the disease known as <i>Myasthenia Gravis</i>, a condition that causes weakness in the muscles that control voluntary movements. The trial is investigating the use of a medication called <i>Cladribine</i>, which is being added to the current treatment plan for patients with a specific type of this disease, known as seropositive myasthenia gravis. The purpose of the study is to evaluate how effective and safe <i>Cladribine</i> is when used in combination with existing treatments.</p>
<p>Participants in the study will receive either <i>Cladribine</i> or a placebo, in addition to their regular treatment. The study will take place over several weeks, during which participants will have regular visits to monitor their health and the effects of the treatment. These visits will include assessments of how the disease affects daily activities and whether there is a need for additional treatments. The study will also look at changes in certain blood markers related to the disease.</p>
<p>Throughout the trial, the safety of the participants will be closely monitored, with regular checks on various health parameters such as blood counts and liver function. The study aims to provide valuable information on whether adding <i>Cladribine</i> to the treatment plan can help improve the management of <i>Myasthenia Gravis</i> and reduce the need for other medications like steroids. The trial is expected to continue until 2026, with the goal of improving treatment options for those affected by this condition.</p>
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