Metastasis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:34:31 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Metastasis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Safety and Effects of THOR-707 and Drug Combination in Adults with Advanced or Metastatic Cancer https://clinicaltrials.eu/trial/study-on-the-safety-and-effects-of-thor-707-and-drug-combination-in-adults-with-advanced-or-metastatic-cancer/ Wed, 29 Apr 2026 14:57:14 +0000 https://clinicaltrials.eu/trial/study-on-the-safety-and-effects-of-thor-707-and-drug-combination-in-adults-with-advanced-or-metastatic-cancer/ This clinical trial is focused on studying the safety and effectiveness of a new treatment called THOR-707 for adults with advanced or metastatic solid tumors, which are types of cancer that have spread to other parts of the body. The study will explore how well THOR-707 works on its own and in combination with other treatments. The main goal is to understand how safe the treatment is and to find the best dose that can be used in future studies.

Participants in the study will receive THOR-707 either by itself or alongside other medications, such as Diphenhydramine, Ondansetron, Dexamethasone, Tocilizumab, Famotidine, and a combination of Buclizine Hydrochloride, Paracetamol, and Codeine Phosphate. Another treatment being tested is Pegenzileukin, which is given through an infusion, meaning it is delivered directly into the bloodstream. Some participants may receive a placebo, which is a substance with no active medication, to compare the effects of the new treatment.

The study will take place over several phases, starting with a dose escalation phase to determine the safest and most effective dose of THOR-707. Participants will be closely monitored for any side effects and the treatment’s impact on their cancer. The study aims to gather information on how the treatment affects tumor growth and overall health. This research is important for developing new cancer treatments and improving outcomes for patients with advanced cancer.

]]>