Metabolic acidosis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Sun, 31 May 2026 04:02:30 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Metabolic acidosis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Effect of sodium hydrogen carbonate on kidney health in critically ill patients with metabolic acidosis and acute kidney injury https://clinicaltrials.eu/trial/effect-of-sodium-hydrogen-carbonate-on-kidney-health-in-critically-ill-patients-with-metabolic-acidosis-and-acute-kidney-injury/ Wed, 29 Apr 2026 15:09:31 +0000 https://clinicaltrials.eu/trial/effect-of-sodium-hydrogen-carbonate-on-kidney-health-in-critically-ill-patients-with-metabolic-acidosis-and-acute-kidney-injury/ This study aims to investigate the effect of sodium hydrogen carbonate on kidney health in patients experiencing metabolic acidosis, which is a condition where there is too much acid in the body fluids, and acute kidney injury, a sudden episode of kidney failure or damage. The research also focuses on individuals suffering from critical illness. Participants will receive a treatment through an intravenous perfusion, which is a method of delivering fluids directly into a vein.

During the study, participants will be given either sodium hydrogen carbonate or a comparison solution containing electrolytes, such as sodium chloride, calcium chloride dihydrate, potassium chloride, or magnesium chloride hexahydrate. These comparison solutions include options like Jonosteril Infusionslösung, Sterofundin ISO Infusionslösung, and Ringer-Infusionslösung B. Braun. The study monitors various health outcomes over a 90-day period, including the need for kidney replacement therapy, which refers to treatments like dialysis that perform the work of the kidneys, and changes in creatinine levels, a substance in the blood used to measure how well the kidneys are functioning.

]]>