Meniere’s disease – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Mon, 03 Aug 2026 10:13:20 +0000 en-US hourly 1 https://wordpress.org/?v=7.1 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Meniere’s disease – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Meniere’s Disease: Comparing Methylprednisolone and Placebo for Patients with Unilateral Meniere’s Disease https://clinicaltrials.eu/trial/study-on-menieres-disease-comparing-methylprednisolone-and-placebo-for-patients-with-unilateral-menieres-disease/ Mon, 03 Aug 2026 10:13:20 +0000 https://clinicaltrials.eu/trial/study-on-menieres-disease-comparing-methylprednisolone-and-placebo-for-patients-with-unilateral-menieres-disease/ This clinical trial is focused on studying the effects of a treatment for Menière’s disease, a condition that affects the inner ear and can cause episodes of vertigo, which is a sensation of spinning or dizziness. The treatment being tested is an injection of methylprednisolone, a type of medication known as a corticosteroid, which is used to reduce inflammation and suppress the immune system. The trial aims to determine if methylprednisolone is more effective than a placebo in reducing the frequency of vertigo attacks in patients with Menière’s disease.

Participants in the study will receive injections directly into the ear, a method known as intratympanic injection. The study will compare the effects of methylprednisolone with those of a placebo over a period of one year. The goal is to see if the treatment can provide better control over vertigo attacks compared to not receiving the active medication. The study will also monitor the quality of life of participants, including aspects related to dizziness and tinnitus, which is a ringing or buzzing noise in one or both ears that may be associated with Menière’s disease.

In addition to methylprednisolone, the study will also consider the use of other medications such as dexamethasone, triamcinolone, and gentamicin, which are also administered through intratympanic injections. The study will track the frequency of these injections and assess their impact on hearing and overall well-being. The trial will also evaluate the use of metoclopramide, a medication that can help manage nausea and vomiting, which are common symptoms during vertigo attacks. The study is designed to provide valuable insights into the effectiveness and safety of these treatments for managing Menière’s disease.

]]> Study on Betahistine Dihydrochloride for Treating Adults with Menière’s Disease https://clinicaltrials.eu/trial/study-on-betahistine-dihydrochloride-for-treating-adults-with-menieres-disease/ Mon, 03 Aug 2026 10:07:37 +0000 https://clinicaltrials.eu/trial/study-on-betahistine-dihydrochloride-for-treating-adults-with-menieres-disease/ This clinical trial is focused on studying Menière’s disease, a condition that can cause symptoms such as dizziness, nausea, ringing in the ears, and hearing loss. The study is comparing two forms of the medication betahistine dihydrochloride. One form is a prolonged-release tablet taken once daily, and the other is a conventional-release tablet taken twice daily. The purpose of the study is to evaluate the effectiveness and safety of these two forms of betahistine in treating Menière’s disease.

Participants in the study will be randomly assigned to one of two groups. One group will receive the prolonged-release form of betahistine, while the other group will receive the conventional-release form. Some participants may also receive a placebo. The study will be conducted over a period of several months, during which participants will take the medication and attend regular check-ups to monitor their symptoms and overall health.

The goal is to determine if the prolonged-release form of betahistine is as effective as the conventional-release form in managing the symptoms of Menière’s disease. Participants’ experiences with vertigo, hearing, and other related symptoms will be closely monitored and recorded throughout the study. This research aims to provide valuable information that could improve treatment options for individuals living with Menière’s disease.

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