Lung assist device therapy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:32:19 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Lung assist device therapy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Comparing low-dose and standard-dose argatroban or enoxaparin to prevent blood clots in patients with heart or lung failure receiving extracorporeal membrane oxygenation. https://clinicaltrials.eu/trial/comparing-low-dose-and-standard-dose-argatroban-or-enoxaparin-to-prevent-blood-clots-in-patients-with-heart-or-lung-failure-receiving-extracorporeal-membrane-oxygenation/ Wed, 29 Apr 2026 15:09:34 +0000 https://clinicaltrials.eu/trial/comparing-low-dose-and-standard-dose-argatroban-or-enoxaparin-to-prevent-blood-clots-in-patients-with-heart-or-lung-failure-receiving-extracorporeal-membrane-oxygenation/ This study is intended to compare different ways of preventing blood clots in patients receiving Extracorporeal Membrane Oxygenation, which is a method used to support the function of the heart and lungs by circulating blood through an external machine. The conditions being studied are Heart Failure and Lung Failure. Participants will receive treatment with either argatroban or enoxaparin through an intravenous infusion, which is a way of delivering medication directly into a vein. Argatroban and enoxaparin are types of anticoagulants, which are substances used to prevent blood from clotting too much.

The study examines whether using a low dose or a standard dose of these medications is safer and more effective. The amount of medication given will be monitored using specific laboratory tests, such as the anti-IIa assay or the anti-Xa assay, which are methods used to measure how well the blood is being thinned. These tests help ensure that the blood does not become too thick, causing clots, or too thin, which could lead to bleeding.

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