Low anterior resection syndrome – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:32:45 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Low anterior resection syndrome – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A study to evaluate the effectiveness of ispaghula husk in patients with low anterior resection syndrome after rectal cancer surgery https://clinicaltrials.eu/trial/a-study-to-evaluate-the-effectiveness-of-ispaghula-husk-in-patients-with-low-anterior-resection-syndrome-after-rectal-cancer-surgery/ Thu, 30 Apr 2026 13:08:53 +0000 https://clinicaltrials.eu/trial/a-study-to-evaluate-the-effectiveness-of-ispaghula-husk-in-patients-with-low-anterior-resection-syndrome-after-rectal-cancer-surgery/ This study focuses on individuals living with Low Anterior Resection Syndrome, which is a group of bowel symptoms that can occur after surgery for rectal cancer. These symptoms often involve changes in bowel habits and bladder control. The purpose of the study is to evaluate the effectiveness of a treatment called Vi-Siblin, which contains ispaghula husk, in managing these symptoms and improving the daily life of patients.

Participants in this research will be assigned to receive either Vi-Siblin granules or a placebo. This is done through a process where neither the participants nor the researchers know which substance is being given. The study involves taking the granules by mouth over a period of time to see how they affect the severity of the symptoms and the overall quality of life.

]]> Study on Improving Bowel Function in Patients with Low Anterior Resection Syndrome Using Glycerol Suppositories or Transanal Irrigation https://clinicaltrials.eu/trial/study-on-improving-bowel-function-in-patients-with-low-anterior-resection-syndrome-using-glycerol-suppositories-or-transanal-irrigation/ Wed, 29 Apr 2026 15:03:49 +0000 https://clinicaltrials.eu/trial/study-on-improving-bowel-function-in-patients-with-low-anterior-resection-syndrome-using-glycerol-suppositories-or-transanal-irrigation/ This clinical trial is focused on helping people who have had surgery for rectal cancer and are experiencing bowel problems afterward, known as Low Anterior Resection Syndrome (LARS). The study is comparing two treatments to see which one works better for improving bowel function and quality of life. One treatment uses glycerol suppositories, which are small, solid forms of medicine inserted into the rectum to help with bowel movements. The other treatment is called transanal irrigation (TAI), a method that involves using water to clean out the lower part of the bowel.

The purpose of the study is to find out if patients who do not see enough improvement with one treatment might benefit more from the other. Participants will first try one of the treatments, and if they do not experience satisfactory improvement, they will switch to the other treatment. The study will monitor changes in bowel function and overall quality of life during this process.

Throughout the study, participants will be asked to report on their symptoms and how they are feeling. This information will help researchers understand which treatment is more effective for managing symptoms of LARS after rectal cancer surgery. The study aims to provide better treatment options for patients dealing with these challenging symptoms.

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