Ligament sprain – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:28:01 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Ligament sprain – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Esflurbiprofen Topical System and Paracetamol for Pain Relief in Patients with Acute Ankle Sprains https://clinicaltrials.eu/trial/study-on-esflurbiprofen-topical-system-and-paracetamol-for-pain-relief-in-patients-with-acute-ankle-sprains/ Wed, 29 Apr 2026 14:22:34 +0000 https://clinicaltrials.eu/trial/study-on-esflurbiprofen-topical-system-and-paracetamol-for-pain-relief-in-patients-with-acute-ankle-sprains/ This clinical trial is focused on studying the treatment of acute ankle sprains, which are injuries that occur when the ankle is twisted or turned in an awkward way, causing pain and swelling. The treatment being tested is called the Esflurbiprofen Topical System (EFTS), which is a patch applied to the skin that contains a medication known as esflurbiprofen. This medication is designed to help reduce pain and inflammation in the affected area. The study will compare the effectiveness of the EFTS patch to a placebo patch, which looks the same but does not contain the active medication.

The purpose of the study is to determine if the EFTS patch is better at reducing pain compared to the placebo patch in people with ankle sprains. Participants in the study will be randomly assigned to receive either the EFTS patch or the placebo patch. They will apply the patch to the affected area and will be monitored over a period of time to assess changes in their pain levels. The study will also involve the use of paracetamol, a common pain reliever, to help manage pain if needed.

Throughout the study, participants will be asked to report their pain levels and any changes they experience. The study aims to gather information on how well the EFTS patch works in reducing pain and improving the ability to move the ankle. The results will help determine if the EFTS patch is a safe and effective treatment option for people with ankle sprains.

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