Labour induction – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Tue, 16 Jun 2026 12:12:07 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Labour induction – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of Oral Misoprostol Combined with Osmotic Dilators for Labour Induction in Women with an Unprepared Cervix https://clinicaltrials.eu/trial/study-of-oral-misoprostol-combined-with-osmotic-dilators-for-labour-induction-in-women-with-an-unprepared-cervix/ Tue, 16 Jun 2026 12:12:07 +0000 https://clinicaltrials.eu/trial/study-of-oral-misoprostol-combined-with-osmotic-dilators-for-labour-induction-in-women-with-an-unprepared-cervix/ The trial focuses on women who need labour induction, a process used when a pregnancy has reached term but labor has not started on its own. The medication being tested is a low‑dose oral tablet called Angusta 25 µg, which contains the active ingredient misoprostol. In addition, small devices known as osmotic dilators are used; they gently expand the cervix by absorbing fluid, helping it become ready for labor.

The purpose of the study is to determine whether giving the tablet and the dilators at the same time reduces the total amount of misoprostol needed compared with giving them one after the other. Women will be randomly assigned to either a concurrent group, where both treatments start together, or a sequential group, where the dilators are placed first and the tablet is added later. The trial is open‑label, meaning both the participants and the health‑care team know which schedule is being used.

During the study, participants will be monitored for the number of tablet doses required, any side effects such as strong uterine contractions (called uterine tachysystole) or infection, and the progress of labor, including how often a vaginal delivery is achieved and whether any surgical delivery is needed. Information about the newborn’s health, such as birth weight and early breathing score, will also be recorded. The study follows the participants from the start of induction until discharge from the hospital after birth.

]]> Study on Misoprostol for Inducing Labor in Pregnant Women: Comparing Outpatient and Inpatient Settings https://clinicaltrials.eu/trial/study-on-misoprostol-for-inducing-labor-in-pregnant-women-comparing-outpatient-and-inpatient-settings/ Wed, 29 Apr 2026 14:26:27 +0000 https://clinicaltrials.eu/trial/study-on-misoprostol-for-inducing-labor-in-pregnant-women-comparing-outpatient-and-inpatient-settings/ This clinical trial is focused on the process of inducing labor, which is when medical methods are used to help start childbirth. The study is examining the use of a medication called misoprostol, which is taken as a tablet. The purpose of the study is to determine if inducing labor at home is as safe and effective as doing it in a hospital setting.

Participants in the study will be randomly assigned to either have their labor induced at home or in the hospital. The study will monitor the safety and effectiveness of both methods by looking at outcomes such as the health of the mother and baby, the method of delivery, and the experiences of the women and their partners. The study will also gather information on the cost-effectiveness of each method and the experiences of healthcare staff involved in the process.

The trial aims to provide valuable insights into whether home-based labor induction can be a safe and effective option for expectant mothers, potentially offering more flexibility and comfort during the childbirth process. The study will continue until the end of 2028, with results being collected and analyzed to help inform future practices in labor induction.

]]> Study on the Effectiveness of Oral Sodium Bicarbonate and Intravenous Hyoscine Butylbromide for Facilitating Natural Childbirth in Pregnant Women Induced for Labor https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-oral-sodium-bicarbonate-and-intravenous-hyoscine-butylbromide-for-facilitating-natural-childbirth-in-pregnant-women-induced-for-labor/ Wed, 29 Apr 2026 14:23:16 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-oral-sodium-bicarbonate-and-intravenous-hyoscine-butylbromide-for-facilitating-natural-childbirth-in-pregnant-women-induced-for-labor/ This clinical trial is focused on studying the process of childbirth, specifically looking at ways to help pregnant women deliver their babies without the need for surgery. The study will test two treatments: oral sodium bicarbonate capsules and intravenous butylscopolamine bromide injections. Sodium bicarbonate is commonly known as baking soda and is used in medicine to neutralize stomach acid. Butylscopolamine bromide, also known as Buscopan, is used to relieve muscle spasms in the stomach and intestines.

The purpose of the study is to see if these treatments can help women who are being induced to go into labor deliver their babies naturally, without needing a cesarean section or other surgical methods. The study will have four groups, with some participants receiving the actual treatments and others receiving a placebo, which looks like the treatment but has no active ingredients. This helps researchers understand the true effects of the treatments.

Participants in the study will be monitored throughout their labor to see if the treatments help in achieving a natural delivery. The study is designed to be double-blind, meaning neither the participants nor the researchers know who is receiving the actual treatment or the placebo, to ensure unbiased results. The trial is expected to continue until early 2025, with the aim of providing valuable insights into improving childbirth outcomes for women undergoing labor induction.

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