Iron deficiency anaemia – European Clinical Trials Information Network

Study on Treating Postoperative Anemia in Older Cardiac Surgery Patients with Ferric Derisomaltose and Sodium Chloride

Wed, 29 Apr 2026 15:00:18 +0000

This clinical trial is focused on studying the treatment of iron deficiency anemia in older patients who have undergone heart surgery. The treatment being tested is an intravenous iron solution called Monofer, which contains the active substance ferric derisomaltose. This solution is given through a vein to help increase iron levels in the body. The study also involves the use of a 0.9% Sodium Chloride Intravenous Infusion Solution, which is a common fluid used in medical settings.

The purpose of the study is to determine how effective the intravenous iron treatment is in reducing disability 90 days after heart surgery. Participants in the study will receive either the iron solution or the sodium chloride solution. The study will monitor the participants’ health and recovery over a period of time to see how the treatment affects their recovery and overall well-being.

Throughout the study, various health indicators will be observed, such as the need for blood transfusions, changes in blood iron levels, and any complications that may arise after surgery. The study aims to provide valuable information on how intravenous iron can help improve recovery in patients with iron deficiency anemia following heart surgery.

Study comparing ferumoxytol and iron sucrose for treating iron deficiency anemia in children

Wed, 29 Apr 2026 15:00:00 +0000

This clinical trial focuses on children with Iron Deficiency Anemia (IDA), a condition where the body doesn’t have enough iron to produce healthy red blood cells. The study will test two medications: ferumoxytol and iron sucrose, which are both given through intravenous administration (directly into a vein).

The main purpose of this research is to evaluate how safe and effective ferumoxytol is for treating children with iron deficiency anemia or who might develop this condition. During the study, participants will receive either ferumoxytol (two doses of 7 mg of iron per kilogram of body weight, up to 510 mg per dose) or iron sucrose (up to 200 mg daily).

The treatment period lasts 5 days, during which doctors will monitor the children’s response to the medication. They will check various health indicators, including the amount of iron in the blood and how well the body is using it. The study will also look at how the medicine moves through the body and how well it is tolerated by the young patients.

Comparing ferumoxytol and iron sucrose for treating iron deficiency anemia in children with chronic kidney disease

Wed, 29 Apr 2026 14:59:49 +0000

This study focuses on children with Chronic Kidney Disease (CKD) who have Iron Deficiency Anemia (IDA) or are at risk of developing it. IDA occurs when the body doesn’t have enough iron to produce adequate amounts of hemoglobin, a protein in red blood cells that carries oxygen throughout the body. The study aims to evaluate how well a medication called ferumoxytol works compared to another iron medication called iron sucrose.

The study will examine the safety and effectiveness of ferumoxytol, which is given as an intravenous solution (delivered directly into a vein). Participants will receive either ferumoxytol or iron sucrose over a period of 5 days. The treatment involves two doses of ferumoxytol or multiple doses of iron sucrose. The study will monitor how these medications affect the iron levels and blood counts in the participants’ bodies.

During the study, doctors will track changes in participants’ blood iron levels and hemoglobin (a protein that carries oxygen in the blood). They will also monitor for any side effects that may occur during or after the treatment. The study will pay special attention to how participants’ bodies respond to both medications, particularly regarding blood pressure and any allergic reactions.

Study on Daily vs. Alternate Day Iron Supplements for Treating Iron Deficiency Anemia in Pregnant Women

Wed, 29 Apr 2026 14:29:20 +0000

This clinical trial is focused on studying iron deficiency anemia in pregnant women. This condition occurs when there is not enough iron in the body to produce the necessary amount of healthy red blood cells, which can lead to fatigue and other health issues. The treatment being tested in this study is Galfer 305mg Hard Capsules, which contain iron and are taken orally. The study aims to compare the effectiveness of taking iron supplements daily versus every other day in improving the health of pregnant women with iron deficiency anemia.

The purpose of the study is to determine if taking iron supplements every other day is just as effective as taking them daily. Participants will be randomly assigned to one of two groups: one group will take the iron supplement every day, while the other group will take it every other day. The study will last for four weeks, during which the participants’ blood levels will be monitored to assess the effectiveness of the treatment. The main focus will be on measuring the hemoglobin levels, which indicate the amount of iron in the blood.

Throughout the study, participants will also be asked about their experiences with the treatment, including any side effects they may encounter. The study will also look at other health outcomes related to pregnancy and delivery. By the end of the study, researchers hope to understand whether taking iron supplements every other day is a viable option for treating iron deficiency anemia in pregnancy, potentially offering a more convenient treatment schedule for expectant mothers.