Intracranial aneurysm – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:25:25 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Intracranial aneurysm – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Iodixanol in Cerebral Angiography for Patients with Unruptured Intracranial Aneurysms https://clinicaltrials.eu/trial/iodixanol-in-cerebral-angiography-for-patients-with-unruptured-intracranial-aneurysms/ Tue, 02 Jun 2026 09:56:41 +0000 https://clinicaltrials.eu/trial/iodixanol-in-cerebral-angiography-for-patients-with-unruptured-intracranial-aneurysms/ This clinical trial is studying intracranial aneurysms, which are weak, bulging areas in the blood vessels inside the brain. The study uses iodixanol, an iodinated contrast medicine given into an artery during cerebral angiography, a type of X-ray test used to look at the blood vessels in the brain. The purpose of the study is to compare different ways of giving this contrast medicine, using lower flow rates and lower volumes, to see whether the images remain clear enough for medical review.

During the study, the contrast medicine is injected through blood vessel access in the neck area, with different injection patterns being compared with the usual method. The examination is done as part of the imaging test, and the pictures are then reviewed. The study also looks at how comfortable the procedure feels, any side effects, and how long the examination takes. No experimental drug other than iodixanol is being tested.

]]> Study on Managing Risk Factors in Patients with Unruptured Brain Aneurysms Using Carbasalate Calcium and Intensive Blood Pressure Treatment https://clinicaltrials.eu/trial/study-on-managing-risk-factors-in-patients-with-unruptured-brain-aneurysms-using-carbasalate-calcium-and-intensive-blood-pressure-treatment/ Wed, 29 Apr 2026 15:01:59 +0000 https://clinicaltrials.eu/trial/study-on-managing-risk-factors-in-patients-with-unruptured-brain-aneurysms-using-carbasalate-calcium-and-intensive-blood-pressure-treatment/ This clinical trial is focused on studying the management of risk factors in patients with unruptured intracranial aneurysms. An aneurysm is a bulge in a blood vessel in the brain that has not burst. The study will use a treatment strategy involving low-dose Acetylsalicylic Acid (commonly known as aspirin) and intensive blood pressure management. The goal is to see if this approach can reduce the risk of the aneurysm growing or rupturing compared to standard care, which typically involves no aspirin and less frequent blood pressure monitoring.

Participants in the study will be randomly assigned to one of two groups. One group will receive low-dose aspirin and will aim to keep their systolic blood pressure (the top number in a blood pressure reading) below 120 mmHg, with weekly checks using a home blood pressure monitor. The other group will receive standard care, which usually involves treating high blood pressure only if it exceeds 140 mmHg, without the use of aspirin or regular home monitoring. The study will last for a period of up to 120 days, during which participants will be monitored for any changes in their aneurysms through imaging tests like MRI or CT scans.

The primary aim of the study is to determine if the new treatment strategy can effectively reduce the risk of aneurysm rupture or growth. Secondary outcomes will also be observed, such as any changes in aneurysm size or shape, the development of new aneurysms, and any related health events like strokes or heart attacks. The study will also assess the overall safety of the treatment and its impact on participants’ quality of life.

]]> Study of acetylsalicylic acid to prevent stroke in patients undergoing brain aneurysm coiling procedure https://clinicaltrials.eu/trial/study-on-acetylsalicylic-acid-for-patients-undergoing-endovascular-coiling-of-unruptured-brain-aneurysms/ Wed, 29 Apr 2026 14:58:27 +0000 https://clinicaltrials.eu/trial/study-on-acetylsalicylic-acid-for-patients-undergoing-endovascular-coiling-of-unruptured-brain-aneurysms/ This clinical trial focuses on patients with unruptured brain aneurysms who are scheduled to undergo a procedure called endovascular coiling, which is a minimally invasive treatment to prevent aneurysm rupture. The study aims to determine if using acetylsalicylic acid (commonly known as aspirin) around the time of the procedure can reduce the occurrence of strokes compared to placebo treatment.

The study medication, Salospir, contains acetylsalicylic acid and will be given by mouth. Participants will receive either acetylsalicylic acid or a placebo in identical-looking capsules. The treatment will last for 5 days, with participants taking one dose daily. The medication or placebo will be given before and after the coiling procedure.

During the study, doctors will monitor participants for any signs of stroke or other complications. Brain imaging using MRI will be performed to check for any small areas of stroke that might not be noticeable to the patient. The study will also track participants’ recovery and brain function for up to one year after the procedure to understand how the treatment affects their overall outcomes.

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