Intervertebral disc degeneration – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 19 Jun 2026 04:02:52 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Intervertebral disc degeneration – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on MSV/AS for Chronic Low Back Pain in Patients with Degenerative Disc Disease Unresponsive to Conventional Therapy https://clinicaltrials.eu/trial/study-on-msv-as-for-chronic-low-back-pain-in-patients-with-degenerative-disc-disease-unresponsive-to-conventional-therapy/ Wed, 29 Apr 2026 14:57:35 +0000 https://clinicaltrials.eu/trial/study-on-msv-as-for-chronic-low-back-pain-in-patients-with-degenerative-disc-disease-unresponsive-to-conventional-therapy/ This clinical trial is focused on studying a condition known as Degenerative Disc Disease, which often causes chronic low back pain. The trial is testing a new treatment using a special type of cell therapy called MSV Allogenic bone marrow stromal mesenchymal cells. These cells are injected into the spine to see if they can help reduce pain and improve the condition of the discs in the spine.

The purpose of the study is to find out if this cell therapy can effectively reduce chronic low back pain and improve the health of the spinal discs in people who have not found relief from other treatments. Participants in the study will receive either the cell therapy or a placebo. The study will last for about 12 months, during which participants will have regular check-ups to monitor their pain levels and the condition of their spinal discs using imaging techniques like Magnetic Resonance Imaging (MRI).

Throughout the study, participants’ overall health, quality of life, and any changes in their use of pain medication will be closely observed. The trial aims to provide valuable information on whether this new treatment can offer a better option for those suffering from chronic low back pain due to Degenerative Disc Disease.

]]> Study on Degenerative Disc Disease: Effects of Autologous Adipose-Derived Mesenchymal Stem Cells in Patients with Degenerative Disc Disease https://clinicaltrials.eu/trial/study-on-degenerative-disc-disease-effects-of-autologous-adipose-derived-mesenchymal-stem-cells-in-patients-with-degenerative-disc-disease/ Wed, 29 Apr 2026 14:23:03 +0000 https://clinicaltrials.eu/trial/study-on-degenerative-disc-disease-effects-of-autologous-adipose-derived-mesenchymal-stem-cells-in-patients-with-degenerative-disc-disease/ This clinical trial is focused on studying degenerative disc disease, a condition that affects the spine and can cause back pain. The treatment being tested involves the use of autologous adipose-derived mesenchymal stem cells, which are special cells taken from a person’s own body fat and then grown in a lab. These cells are prepared as a suspension for injection and are given to patients through a procedure called intradiscal use, which means they are injected directly into the affected disc in the spine.

The purpose of the study is to observe how patients respond to this stem cell therapy and to monitor any potential side effects. Participants in the study will be divided into two groups: one receiving the stem cell treatment and the other serving as a control group, which may receive a placebo. The study will track the success of the treatment by looking at pain reduction and other health measures over a period of two years. This includes keeping a pain diary and using various health questionnaires like the VAS-score and EQ-5D to assess the patient’s quality of life and pain levels.

Throughout the study, researchers will also use MRI scans to examine changes in the discs, such as their height and water content. The trial aims to provide valuable insights into whether this stem cell therapy can effectively regenerate intervertebral discs and improve symptoms for those suffering from degenerative disc disease.

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