Intellectual disability – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:36:11 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Intellectual disability – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of Oxytocin Nasal Spray as Add-on Treatment for Children with Autism Spectrum Disorder and Intellectual Disability: Safety and Feasibility Assessment https://clinicaltrials.eu/trial/study-on-oxytocin-and-sodium-chloride-for-managing-challenging-behaviors-in-children-with-autism-and-intellectual-disability/ Wed, 29 Apr 2026 14:59:39 +0000 https://clinicaltrials.eu/trial/study-on-oxytocin-and-sodium-chloride-for-managing-challenging-behaviors-in-children-with-autism-and-intellectual-disability/ This study focuses on children with Autism Spectrum Disorder who also have moderate to severe intellectual disability. The research examines the use of oxytocin nasal spray alongside standard behavioral and educational therapy. Oxytocin is a naturally occurring hormone that may help improve social interaction and behavior in children with autism.

The study aims to determine if it is practical and safe to use oxytocin nasal spray in children aged 6 to 12 years who have severe autism and significant intellectual challenges. During the study, participants will receive either oxytocin nasal spray or a placebo (containing sodium chloride) in addition to their regular therapy. The treatment will be given daily through a nasal spray both at treatment centers and at home.

The treatment period lasts up to 12 weeks, during which children will receive regular medical check-ups. The study will test two different doses of oxytocin (4 and 8 international units) to evaluate how well children tolerate the treatment. Throughout the study, healthcare providers and parents will monitor the children’s response to the treatment and any changes in their behavior.

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